RATING IMPAIRMENT AND DISABILITY IN PARKINSONS-DISEASE - EVALUATION OF THE UNIFIED PARKINSONS-DISEASE RATING-SCALE
RATING IMPAIRMENT AND DISABILITY IN PARKINSONS-DISEASE - EVALUATION OF THE UNIFIED PARKINSONS-DISEASE RATING-SCALE
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DOI：
10.1002/mds.870090113
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发表时间：
1994-01-01
影响因子：
8.6
通讯作者：
ROOS, RAC
中科院分区：
文献类型：
--
作者：
VANHILTEN, JJ;VANDERZWAN, AD;ROOS, RAC
尽管统一帕金森病评定量表（UPDRS）广泛用于监测疾病进展和药物疗效，但尚未尝试评估其科学和临床质量。日常生活活动 (ADL) 部分中项目的临床敏感性差以及运动检查 (ME) 部分中项目的冗余促使我们确定是否可以将这些部分中的项目数量减少到更小、同样敏感的集合，从而与原始项目集一样可靠地描述数据。因此，我们根据 UPDRS 以及 Hoehn 和 Yahr 分期量表对 111 名特发性帕金森病患者进行了评估。我们的结果表明，ADL（13 个项目）和 ME（14 个项目）部分可以减少到各 8 个项目，而不会损失可靠性或有效性。我们的报告是初步的，需要验证。
Although the Unified Parkinson's Disease Rating Scale (UPDRS) is widely used to monitor disease progression and drug efficacy, no attempts have been made to evaluate its scientific and clinical quality. Poor clinical sensibility of items in the activities of daily living (ADL) section and redundancy of items in the motor examination (ME) section prompted us to determine if the number of items in these sections could be reduced to a smaller, equally sensitive set that would describe the data as reliably as did the original set of items. Therefore, we assessed 111 patients with idiopathic Parkinson's disease on the UPDRS and Hoehn and Yahr staging scales. Our results show that the ADL (13 items) and ME (14 items) sections can be reduced to 8 items each without loss of reliability or validity. Our report is preliminary and needs validation.