Home-based walking exercise intervention in peripheral artery disease: a randomized clinical trial.
Home-based walking exercise intervention in peripheral artery disease: a randomized clinical trial.
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家庭徒步运动干预外周动脉疾病：一项随机临床试验。
DOI：
10.1001/jama.2013.7231
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发表时间：
2013-07-03
期刊：
影响因子：
--
通讯作者：
Rejeski WJ
中科院分区：
文献类型：
--
作者：
McDermott MM;Liu K;Guralnik JM;Criqui MH;Spring B;Tian L;Domanchuk K;Ferrucci L;Lloyd-Jones D;Kibbe M;Tao H;Zhao L;Liao Y;Rejeski WJ
临床实践指南指出，没有足够的证据支持建议外周动脉疾病（PAD）患者参加家庭步行锻炼计划。确定与健康教育对照组相比，采用团体介导的认知行为干预（结合团体支持和自我调节技能）的家庭步行锻炼计划是否可以改善伴有和不伴有间歇性跛行的PAD患者的功能表现。2008年7月22日至2012年12月14日在伊利诺伊州芝加哥进行的194例PAD患者（包括72.2%无间歇性跛行典型症状的患者）的随机对照临床试验。参与者被随机分配到2个平行组中的1个：以家庭为基础的组介导的认知行为步行干预或注意力控制条件。主要结局是6分钟步行能力的6个月变化。次要结果包括6个月跑步机步行、体力活动、步行障碍问卷（WIQ）和12项简表健康调查的身心健康综合评分的变化。随机分配到干预组的参与者显著增加了他们的6分钟步行距离（[以米为单位报告] 357.4至399.8 vs对照组353.3至342.2;平均差异，53.5 [95% CI，33.2至73.8]; P < .001），最大踏车行走时间（干预组，7.91 - 9.44分钟vs对照组，7.56 - 8.09;平均差异，1.01分钟[95% CI，0.07 - 1.95]; P = .04），7天内加速度计测量的身体活动（干预组：778.0 ~ 866.1 vs对照组：671.6 ~ 645.0;平均差异：114.7活动单位[95%CI：12.82 ~ 216.5]; P = .03），WIQ距离评分（干预组，35.3 - 47.4 vs对照组，33.3 - 34.4;平均差异，11.1 [95% CI，3.9 - 18.1]; P = .003），WIQ速度评分（干预组，36.1 - 47.7 vs对照组，35.3-36.6;平均差异，10.4 [95%CI，3.4 - 17.4]; P = 0.004）。在有和没有典型跛行症状的PAD参与者中，以家庭为基础的步行锻炼计划显着改善了步行耐力，身体活动和患者感知的步行耐力和速度。这些发现对大量无法或不愿意参加监督锻炼计划的PAD患者具有影响。clinicaltrials.gov标识符：NCT 00693940
Clinical practice guidelines state there is insufficient evidence to support advising patients with peripheral artery disease (PAD) to participate in a home-based walking exercise program. To determine whether a home-based walking exercise program that uses a group-mediated cognitive behavioral intervention, incorporating both group support and self-regulatory skills, can improve functional performance compared with a health education control group in patients with PAD with and without intermittent claudication. Randomized controlled clinical trial of 194 patients with PAD, including 72.2% without classic symptoms of intermittent claudication, performed in Chicago, Illinois between July 22, 2008, and December 14, 2012. Participants were randomized to 1 of 2 parallel groups: a home-based group-mediated cognitive behavioral walking intervention or an attention control condition. The primary outcome was 6-month change in 6-minute walk performance. Secondary outcomes included 6-month change in treadmill walking, physical activity, the Walking Impairment Questionnaire (WIQ), and Physical and Mental Health Composite Scores from the 12-item Short-Form Health Survey. Participants randomized to the intervention group significantly increased their 6-minute walk distance ([reported in meters] 357.4 to 399.8 vs 353.3 to 342.2 for those in the control group; mean difference, 53.5 [95% CI, 33.2 to 73.8]; P < .001), maximal treadmill walking time (intervention, 7.91 to 9.44 minutes vs control, 7.56 to 8.09; mean difference, 1.01 minutes [95% CI, 0.07 to 1.95]; P = .04), accelerometer-measured physical activity over 7 days (intervention, 778.0 to 866.1 vs control, 671.6 to 645.0; mean difference, 114.7 activity units [95% CI, 12.82 to 216.5]; P = .03), WIQ distance score (intervention, 35.3 to 47.4 vs control, 33.3 to 34.4; mean difference, 11.1 [95% CI, 3.9 to 18.1]; P = .003), and WIQ speed score (intervention, 36.1 to 47.7 vs control, 35.3–36.6; mean difference, 10.4 [95% CI, 3.4 to 17.4]; P = .004). A home-based walking exercise program significantly improved walking endurance, physical activity, and patient-perceived walking endurance and speed in PAD participants with and without classic claudication symptoms. These findings have implications for the large number of patients with PAD who are unable or unwilling to participate in supervised exercise programs. clinicaltrials.gov Identifier: NCT00693940
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影响因子：
24
作者：
McDermott, Mary M.;Liu, Kiang;Criqui, Michael H.
通讯作者：
Criqui, Michael H.
DOI：
10.1046/j.1532-5415.2001.49151.x
发表时间：
2001-06-01
影响因子：
6.3
作者：
McDermott, MM;Ohlmiller, SM;Greenland, P
通讯作者：
Greenland, P
影响因子：
5.7
作者：
McDermott, MM;Hahn, EA;Hudgens, S
通讯作者：
Hudgens, S
影响因子：
3.5
作者：
Hirsch, AT;Halverson, SL;Hunninghake, DB
通讯作者：
Hunninghake, DB
DOI：
10.1249/00005768-198205000-00012
发表时间：
1982-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
BORG, GAV
通讯作者：
BORG, GAV