SECONDARY DISEASE OF RADIATION CHIMERAS - A SYNDROME DUE TO LYMPHOID APLASIA

SECONDARY DISEASE OF RADIATION CHIMERAS - A SYNDROME DUE TO LYMPHOID APLASIA
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DOI：
10.1111/j.1749-6632.1962.tb45321.x
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发表时间：
1962-01-01
期刊：
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES
影响因子：
--
通讯作者：
MICKLEM, HS
MICKLEM, HS
中科院分区：
其他
文献类型：
--
作者：
BARNES, DWH;LOUTIT, JF;MICKLEM, HS

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继发病不一定依赖移植物抗宿主免疫反应。而且，相容性淋巴细胞在减轻继发病方面的重要性至少与不相容性淋巴细胞在引发继发病方面的重要性相当。此外，如果抗原差异程度较小，在这种情况下同种异体淋巴细胞不一定表现为不相容。
Secondary disease does not necessarily depend on a graft-versus-host immune reaction. Also compatible lymphoid cells are at least as important in reducing secondary disease as incompatible lymphoid cells are in causing it. Moreover, allogeneic lymphoid cells need not behave as incompatible in this situation if the degree of antigenic difference is small.