Industry-sponsored research in developing countries
Industry-sponsored research in developing countries
复制标题
DOI：
10.1016/j.cct.2007.02.011
复制
发表时间：
2007-11-01
影响因子：
2.2
通讯作者：
Abbas, E. E.
中科院分区：
文献类型：
--
作者：
Abbas, E. E.
背景：工业已经成为临床研究的重要资金来源；发展中国家关于工业和医疗机构之间关系的指导方针尚不明确，因此我们想测试这些国家的态度和做法，并将其与发达国家进行比较。我们在发达国家和代表发展中国家的阿拉伯国家的医生中进行了一项调查，以记录他们对行业赞助的研究和他们在这方面的实际实践的看法。方法：通过电子邮件、邮件和个人接触的方式发放结构化问卷。问卷包括所涉从业者的特征、他们对行业赞助研究的态度以及他们的实际做法。问卷发放给了两组国家的510名医生。代表发达国家的从业人员来自美国、英国、澳大利亚和新西兰。代表发展中国家的包括来自亚洲和非洲的阿拉伯国家。结果：我们发现，尽管两组中都有超过80%的人认为有必要进行行业资助的研究，但两组人的观点和做法存在差异。69.7%的发达国家受访者参与了行业赞助的研究，而发展中国家只有30.1%的受访者参与了这一研究。发达国家比发展中国家更好地遵守了这类研究的指导方针。在发达国家没有不参与调查人员的作者的情况下，发展中国家16.3%的行业赞助研究包括不属于调查人员的作者。发达国家和发展中国家分别有94%和58%的机构设有研究伦理委员会。在发达国家和发展中国家，57%和41%的国家有审查机构。结论：行业赞助的研究是必要的；这种情况在发达国家更为常见。发展中国家应通过关于行业赞助研究的明确指导方针，包括设立研究伦理委员会和审查机构来监督这类研究。(C)2007 Elsevier Inc.保留所有权利。
Background: Industry has become an important source of funding for clinical research; guidelines governing the relationship between industry and medical institutions are not clear in developing countries and hence we wanted to test attitudes and practices in those countries and compare them to developed countries. We conducted a survey amongst medical practitioners in developed and Arab countries representing developing countries, in order to document their views towards industry-sponsored research and their actual practice in this regard.Methods: A structured questionnaire was distributed by email, mail and through personal contacts. The questionnaire included information on characteristics of the practitioners involved, their attitudes towards industry-sponsored research and their actual practices. The questionnaire was distributed to 5 10 medical practitioners of countries in both groups. Practitioners representing developed countries were from the United States, United Kingdom, Australia and New Zealand. Those representing developing countries included Arab countries from Asia and Africa.Results: We found that there were contrasting views and practices between the two groups although more than 80% in both groups agreed that industry-sponsored research is necessary. 69.7% of respondents in developed countries participated in industry-sponsored research while only 30.1% did so in developing countries. Guidelines governing such research were better adhered to in developed countries than in developing countries. Where there were no authors who were not part of investigators in developed countries, 16.3% of industry-sponsored research in developing countries included authors who were not part of the investigators. Research ethics committees were present in 94% and 58% of institutions in developed and developing countries respectively. Review bodies were available in 57% and 41% in developed and developing countries.Conclusions: Industry-sponsored research is necessary; it is much more common in developed countries. Clear guidelines governing industry-sponsored research should be adopted in developing countries, including the establishment of research ethics committees and review bodies to monitor such research. (c) 2007 Elsevier Inc. All rights reserved.