Abstract P072: Low-Carbohydrate-Diets and Cardiovascular and Total Mortality in Japanese. A 29-year Follow-up of NIPPON DATA80
Abstract P072: Low-Carbohydrate-Diets and Cardiovascular and Total Mortality in Japanese. A 29-year Follow-up of NIPPON DATA80
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摘要 P072：日本人的低碳水化合物饮食与心血管死亡率和总死亡率。
DOI：
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
H. Ueshima
中科院分区：
文献类型：
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作者：
Yasuyuki Nakamura;N. Okuda;T. Okamura;A. Kadota;N. Miyagawa;T. Hayakawa;Y. Kita;A. Fujiyoshi;M. Nagai;N. Takashima;T. Ohkubo;K. Miura;A. Okayama;H. Ueshima
背景：亚洲人群碳水化合物摄入量相对较高，长期低碳水化合物饮食的安全性尚不清楚。研究方法：我们使用NIPPON DATA80数据库，对低碳水化合物饮食与CVD和总死亡率的关系进行了29年随访。在1980年基线时，从日本随机选择的地区收集年龄≥30岁的研究参与者的数据。我们计算低碳水化合物饮食分数的基础上的能量的百分比，碳水化合物，脂肪和蛋白质，估计3天称重的食物记录。我们随访了9，200名参与者（56%为女性，平均年龄51岁）。结果：在随访期间，有1，171例CVD死亡（女性占52%），3，443例死亡（女性占48%）。采用比较低碳水化合物饮食评分最高与最低十分位数的考克斯模型，CVD死亡率的多变量校正风险比（HR）为0.59（95%可信区间）。
Background: Long-term safety of low-carbohydrate-diets in Asian populations, whose carbohydrate intake is relatively high, is not known. Methods: We examined the association of low-carbohydrate-diets with CVD and total mortality using the National Integrated Project for Prospective Observation of Noncommunicable Disease and Its Trends in the Aged, (NIPPON DATA80) database with a 29-year follow-up. At the baseline in 1980, data were collected on study participants ages≥30 years from randomly selected areas in Japan. We calculated low-carbohydrate-diet scores based on the percentage of energy as carbohydrate, fat, and protein, estimated by 3-day weighed food records. We followed 9,200 participants (56% women, mean age 51 y). Results: During the follow-up, there were 1,171 CVD deaths (52% in women), and 3,443 total deaths (48% in women). The multivariate-adjusted hazard ratio (HR) for CVD mortality using the Cox model comparing highest versus lowest deciles for a low-carbohydrate-diet score was 0.59 (95% con...