Cyclodextrin-Based Microcapsules as Bioreactors for ATP Biosynthesis
Cyclodextrin-Based Microcapsules as Bioreactors for ATP Biosynthesis
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基于环糊精的微胶囊作为 ATP 生物合成的生物反应器
DOI：
10.1021/bm400584h
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发表时间：
2013-09-01
影响因子：
6.2
通讯作者：
Zhang, Sheng
中科院分区：
文献类型：
--
作者：
Li, Jian-Hu;Wang, Yi-Fu;Zhang, Sheng
通过将 CF0F1-ATPase 组装在由 α-环糊精/壳聚糖接枝聚（乙二醇）甲基丙烯酸酯组成的脂质涂层中空纳米胶囊上，制备了仿生能量转换器。将GOD捕获到这些胶囊中后，添加葡萄糖可以触发质子动力，然后驱动ATP酶旋转以合成ATP。
A biomimetic energy converter was fabricated via the assembly of CF0F1-ATPase on lipid-coated hollow nanocapsules composed of alpha-cyclodextrins/chitosan-graft-poly(ethylene glycol) methacrylate. Upon entrapped GOD into these capsules, the addition of glucose could trigger proton-motive force and then drive the rotation of ATPase to synthesize ATP.