Cigarette smoking in relation to the risk of myocardial infarction in young women. Modifying influence of age and predisposing factors.
Cigarette smoking in relation to the risk of myocardial infarction in young women. Modifying influence of age and predisposing factors.
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吸烟与年轻女性心肌梗死的风险有关。
DOI：
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发表时间：
1980
影响因子：
7.7
通讯作者：
P. Stolley
中科院分区：
文献类型：
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作者：
L. Rosenberg;Samuel Shapiro;David W. Kaufman;Sdennis Slone;Olli S. Miettinen;P. Stolley
我们评估了30-49岁女性的心肌梗死(MI)与吸烟的关系。在318名首次心肌梗死后存活的女性和1272名年龄匹配的对照组中，吸烟者的比例分别为83%和54%(p<；0.001)。估计的相对风险随着吸烟量的增加而递增：与从不吸烟的女性相比，每天吸烟15支以下的吸烟者的估计相对风险为1.8，每天35支或更多香烟的吸烟者的估计相对风险为6.9。在每种程度的吸烟中，风险的相对增加在较年轻的年龄和那些没有明显易受其他因素影响的人中更大。尽管心肌梗塞在年轻女性中是一种罕见的疾病，但我们的数据表明，那些吸烟严重的人面临的风险是可以察觉的。
We evaluated the relation between myocardial infarction (MI) and cigarette smoking in women 30 to 49 years of age. Among 318 women who had survived recent first infarctions and 1272 age-matched controls, the proportions of cigarette smokers were 83% and 54%, respectively (p < 0.001). The estimated relative risk rose progressively with amount smoked: compared with women who had never smoked, the estimate was 1.8 for smokers of less than 15 cigarettes per day and 6.9 for smokers of 35 or more cigarettes per day. At each level of smoking, the relative increase in risk was greater at younger ages and among those not apparently predisposed from other factors. Although MI is a rare disease in young women, our data indicate that the risks faced by those who smoke heavily are appreciable.