Dementia screening questionnaire for individuals with intellectual disabilities
Dementia screening questionnaire for individuals with intellectual disabilities
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DOI：
10.1192/bjp.bp.106.024984
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发表时间：
2007-05-01
影响因子：
10.5
通讯作者：
Bhaumik, Sabyasachi
中科院分区：
文献类型：
--
作者：
Deb, Shoumitro;Hare, Monika;Bhaumik, Sabyasachi
背景 许多患有唐氏综合症的成年人相对较早地患上阿尔茨海默氏痴呆，但准确的临床诊断仍然很困难。目的是为智障成年人开发一种用户友好的观察者评级的痴呆筛查问卷，具有很强的心理测量特性。方法我们使用定性方法从唐氏综合症患者的护理人员那里收集有关痴呆症状的信息。这为智力障碍者痴呆症筛查问卷 (DSQIID) 提供了项目，然后我们对其心理测量特性进行了测试。结果 DSQIID 对 193 名患有唐氏综合症的成年人的护理人员进行了测试，其中 117 名患者接受了临床医生的检查，根据修订后的 ICD-10 标准，确认了 49 名患者的痴呆症诊断。我们确定总分 20 为筛查提供了最大灵敏度 (0.92) 和最佳特异性 (0.97)。 DSQIID 的所有 53 个项目均具有良好的内部一致性（alpha = 0.91），并且具有良好的重测和参与者间信度。我们通过将项目分为四个因素，建立了良好的结构效度。结论 DSQIID 是一种有效、可靠且用户友好的观察者评分问卷，用于筛查成人唐氏综合症痴呆症。
Background Many adults with Down's syndrome develop Alzheimer's dementia relatively early in their lives, but accurate clinical diagnosis remains difficult.Aims To develop a user-friendly observer-rated dementia screening questionnaire with strong psychometric properties for adults with intellectual disabilities.Method We used qualitative methods to gather information from carers of people with Down's syndrome about the symptoms of dementia. This provided the items for the Dementia Screening Questionnaire for Individuals with Intellectual Disabilities (DSQIID), which we then tested for its psychometric properties.Results The DSQIID was administered to carers of 193 adults with Down's syndrome, 117 of whom were examined by clinicians who confirmed a diagnosis of dementia for 49 according to modified ICD-10 criteria. We established that a total score of 20 provides maximum sensitivity (0.92) and optimum specificity (0.97) for screening. The DSQIID has sound internal consistency (alpha=0.91) for all its 53 items, and good test-retest and interrater reliability We established a good construct validity by dividing the items into four factors.Conclusions The DSQIID is a valid, reliable and user-friendly observer-rated questionnaire for screening for dementia among adults with Down's syndrome.