Ocular response analyzer versus Goldmann applanation tonometry for intraocular pressure measurements
Ocular response analyzer versus Goldmann applanation tonometry for intraocular pressure measurements
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DOI：
10.1167/iovs.06-0158
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发表时间：
2006-10-01
影响因子：
4.4
通讯作者：
Garcia-Sanchez, Julian
中科院分区：
文献类型：
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作者：
Martinez-de-la-Casa, Jose M.;Garcia-Feijoo, Julian;Garcia-Sanchez, Julian
目的.建立眼反应分析仪（ORA）和Goldmann压平眼压计（GAT）测量的眼内压（IOP）之间的相关性。还检查了中央角膜厚度对测量结果的影响。这是一项横断面研究。对48例48眼青光眼患者的眼压进行了测定。所有患者均用超声角膜厚度测量仪测量中央角膜厚度（CCT）。ORA读数始终高于GAT测量值（Goldmann相关IOP-IOP GAT平均差，7.2 ± 3.5 mm Hg;角膜代偿性IOP-IOP GAT平均差异，8.3 +/- 4.0 mm Hg）然而，差异不是恒定的，并且随着IOP GAT读数的增加而增加，这两种差异都与Goldmann相关IOP有关（斜率= 0.623，P < 0.0001）和角膜代偿性IOP（斜率= 0.538，P < 0.0001）。ORA提供的两个压力测量值均显示与CCT显著相关（CCT与Goldmann相关IOP：r = 0.460，P = 0.001; CCT与角膜代偿IOP：r = 0.442，P = 0.001）。角膜曲率或屈光度对任何压力均无显著影响。与GAT相比，ORA显著高估IOP。两组测量值之间的差异随着GAT确定的IOP增加而增加。ORA读数似乎受到中央角膜厚度的影响。
PURPOSE. To establish correlations between intraocular pressure (IOP) measurements obtained with the ocular response analyzer (ORA) and the Goldmann applanation tonometer ( GAT). The effects of central corneal thickness on the measures obtained were also examined.METHODS. This was a cross-sectional study. IOP was determined in 48 eyes of 48 patients with glaucoma In all patients, central corneal thickness (CCT) was measured by ultrasound pachymetry.RESULTS. ORA readings were consistently higher than GAT measurements (Goldmann-correlated IOP-IOP GAT mean difference, 7.2 +/- 3.5 mm Hg; corneal-compensated IOP-IOP GAT mean difference, 8.3 +/- 4.0 mm Hg) However, differences were not constant and increased with increasing IOP GAT readings, both with respect to Goldmann-correlated IOP (slope = 0.623, P < 0.0001) and corneal- compensated IOP (slope = 0.538, P < 0.0001). Both pressure measurements provided by the ORA showed significant correlation with CCT (CCT versus Goldmann-correlated IOP: r = 0.460, P = 0.001; CCT versus corneal- compensated IOP: r = 0.442, P = 0.001). No significant effects of corneal curvature or refraction on any of the pressures were observed.CONCLUSIONS. The ORA significantly overestimates IOP compared with the GAT. Differences between both sets of measures increase as the GAT-determined IOP increases. ORA readings seem to be affected by central corneal thickness.