Potent Phytotoxic Harziane Diterpenes from a Soft Coral-Derived Strain of the Fungus Trichoderma harzianum XS-20090075

Potent Phytotoxic Harziane Diterpenes from a Soft Coral-Derived Strain of the Fungus Trichoderma harzianum XS-20090075
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来自软珊瑚衍生真菌哈茨木霉 XS-20090075 菌株的强效植物毒性哈茨二萜

DOI:
10.1038/s41598-019-49778-7
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发表时间:
2019-09-16
期刊:
影响因子:
4.6
通讯作者:
Wang, Chang-Yun
Wang, Chang-Yun
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zhao, Dong-Lin;Yang, Lu-Jia;Wang, Chang-Yun

文献摘要

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Two new harziane diterpene lactones, possessing a 6/5/7/5-fused carbocyclic core containing a lactone ring system, harzianelactones A and B (l and 2), and five new harziane diterpenes, harzianones A-D (3-6) and harziane (7), were isolated from the soft coral-derived fungus Trichoderma harzianum XS-20090075. Their structures were determined by extensive NMR spectroscopic data, ECD and OR calculations, as well as X-ray diffraction. The isolated compounds exhibited potent phytotoxicity against seedling growth of amaranth and lettuce. Harziane diterpenes were rarely reported for their remarkably bioactivities, and it was the first report to study the phytotoxicity of harziane diterpenes, which provide a new application of such compounds in agriculture for future research.