Initial Weight Loss Response as an Indicator for Providing Early Rescue Efforts to Improve Long-term Treatment Outcomes.
Initial Weight Loss Response as an Indicator for Providing Early Rescue Efforts to Improve Long-term Treatment Outcomes.
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DOI：
10.1007/s11892-017-0904-1
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发表时间：
2017-09
影响因子：
4.2
通讯作者：
Dorfman L
中科院分区：
文献类型：
--
作者：
Unick JL;Pellegrini CA;Demos KE;Dorfman L
对行为减肥（WL）计划的反应存在很大差异。降低肥胖和糖尿病的发生率可能需要更多的人在治疗后达到具有临床意义的 WL。鉴于 WL 计划前 1-2 个月内的 WL 与长期 WL 相关，通过识别初始成功率较差的患者（即“早期无反应者”）并向其提供额外干预，可能会改善治疗结果。我们回顾了有关早期无反应 WL 计划的最新文献，并讨论了如何利用适应性干预作为“拯救”早期无反应者的策略。初步研究结果表明，适应性干预措施，特别是阶梯式护理方法，有望改善早期无反应者的预后。未来的研究需要确定干预的最佳时间点和阈值以及采用的早期干预类型。临床医生和研究人员在做出治疗决定时应考虑讨论的因素。
There is large variability in response to behavioral weight loss (WL) programs. Reducing rates of obesity and diabetes may require more individuals to achieve clinically significant WL post-treatment. Given that WL within the first 1–2 months of a WL program is associated with long-term WL, it may be possible to improve treatment outcomes by identifying and providing additional intervention to those with poor initial success (i.e., ‘early non-responders’). We review the current literature regarding early non-response to WL programs and discuss how adaptive interventions can be leveraged as a strategy to ‘rescue’ early non-responders. Preliminary findings suggest that adaptive interventions, specifically stepped-care approaches, offer promise for improving outcomes among early non-responders. Future studies need to determine the optimal time point and threshold for intervening and the type of early intervention to employ. Clinicians and researchers should consider the discussed factors when making treatment decisions.
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影响因子：
3.1
作者：
Carels, Robert A.;Wott, Carissa B.;Koball, Afton
通讯作者：
Koball, Afton
影响因子：
7.9
作者：
Stotland, SC;Larocque, M
通讯作者：
Larocque, M
影响因子：
120.7
作者：
Mokdad, AH;Ford, ES;Marks, JS
通讯作者：
Marks, JS
影响因子：
2.2
作者：
Sherwood NE;Butryn ML;Forman EM;Almirall D;Seburg EM;Lauren Crain A;Kunin-Batson AS;Hayes MG;Levy RL;Jeffery RW
通讯作者：
Jeffery RW
DOI：
10.1038/ijo.2015.89
发表时间：
2015-10
期刊：
International journal of obesity (2005)
影响因子：
--
作者：
Unick JL;Leahey T;Kent K;Wing RR
通讯作者：
Wing RR