Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex
Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex
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光促进镍催化：NiII-芳基配合物催化芳基亲电子试剂与醇的醚化
DOI：
10.1002/anie.202003359
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Dong Xue
中科院分区：
文献类型：
--
作者：
Liu Yang;Huan-Huan Lu;Chu-Hui Lai;Gang Li;Wei Zhang;Rui Cao;Fengyi Liu;Chao Wang;Jianliang Xiao;Dong Xue
A highly effective C−O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII‐aryl complex under long‐wave UV (390–395 nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C−O coupling is also possible. The reaction appears to proceed via a NiI–NiIIIcatalytic cycle.
