Diffusion-weighted imaging of patients with neonatal bilirubin encephalopathy

Diffusion-weighted imaging of patients with neonatal bilirubin encephalopathy
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DOI:
10.1007/s11604-012-0166-4
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发表时间:
2013-03-01
影响因子:
2.1
通讯作者:
Karakas, Omer
Karakas, Omer
中科院分区:
医学4区
文献类型:
--
作者:
Cece, Hasan;Abuhandan, Mahmut;Karakas, Omer

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为探讨DWI对新生儿胆红素脑病急性期的诊断价值,选择30例胎龄38-40周的高胆红素血症新生儿为研究对象,另取24例年龄、体重、胎龄均相等的新生儿为对照组。对新生儿胆红素脑病组和对照组进行DWI检查,比较两组新生儿胆红素脑病组和对照组的DWI表观扩散系数(ADC)值,发现新生儿胆红素脑病组的ACD值明显高于对照组(p < 0.001)。新生儿胆红素值与DWI表现有显著相关性(r = 0.41,p < 0.05),ADC值可作为新生儿胆红素脑病的诊断指标。
The aim of the study is to evaluate neonatal bilirubin encephalopathy in the acute period by the DWI.Thirty newborn babies with hyperbilirubinemia at the gestational age of 38-40 weeks, diagnosed with acute neonatal bilirubin encephalopathy as a result of clinical findings were included in the study, and a further 24 newborn babies, whose ages, weights and gestational ages were equalized, were regarded as a control group. DWI was performed on both patient and control groups.When DWI apparent diffusion coefficients (ADC) of both neonatal bilirubin encephalopathy patients and the control group were compared, ACD values of neonatal bilirubin encephalopathy patients were found to be statistically significantly highly compared to that of the control group (p < 0.001). There was a significant correlation between bilirubin values and DWI findings (r = 0.41, p < 0.05).The ADC measurement could be a promising parameter in detecting neonatal bilirubin encephalopathy.