Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017.
Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017.
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DOI：
10.2807/1560-7917.es.2018.23.46.1800516
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发表时间：
2018-11
期刊：
影响因子：
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通讯作者：
Healthcare-Associated Infections Prevalence Study Group
中科院分区：
文献类型：
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作者：
Suetens C;Latour K;Kärki T;Ricchizzi E;Kinross P;Moro ML;Jans B;Hopkins S;Hansen S;Lyytikäinen O;Reilly J;Deptula A;Zingg W;Plachouras D;Monnet DL;Healthcare-Associated Infections Prevalence Study Group
2016年至2017年，欧盟和欧洲经济区（EU/EEA）的医疗相关感染（HAI）和抗菌药物使用的点患病率调查包括来自28个国家的1，209家急性护理医院（ACH）的310，755名患者和来自23个国家的2，221家长期护理机构（LTCF）的117，138名居民。在国家验证后，我们估计ACH中6.5%（累积95%置信区间（cCI）：5.4-7.8%）的患者和LTCF中3.9%（95% cCI：2.4-6.0%）的居民至少有一次HAI（国家加权患病率）。在任何给定日期，ACH中98，166例患者（95% cCI：81，022 - 117，484）和LTCF中129，940例居民（95% cCI：79，570 - 197，625）发生HAI。每年HAI发作估计为890万（95% cCI：460 - 1560万），包括450万（95% cCI：260 - 760万）例ACH和440万（95% cCI：200 - 800万）例LTCF;每年有380万（95% cCI：310 - 450万）例ACH患者发生HAI。对选定AMR标志物的抗菌药物耐药（AMR）在ACH中为31.6%，在LTCF中为28.0%。我们的研究证实了欧盟/欧洲经济区医疗机构每年的HAI数量很高，并表明LTCF中HAI的AMR可能已达到与ACH相同的水平。
Point prevalence surveys of healthcare-associated infections (HAI) and antimicrobial use in the European Union and European Economic Area (EU/EEA) from 2016 to 2017 included 310,755 patients from 1,209 acute care hospitals (ACH) in 28 countries and 117,138 residents from 2,221 long-term care facilities (LTCF) in 23 countries. After national validation, we estimated that 6.5% (cumulative 95% confidence interval (cCI): 5.4–7.8%) patients in ACH and 3.9% (95% cCI: 2.4–6.0%) residents in LTCF had at least one HAI (country-weighted prevalence). On any given day, 98,166 patients (95% cCI: 81,022–117,484) in ACH and 129,940 (95% cCI: 79,570–197,625) residents in LTCF had an HAI. HAI episodes per year were estimated at 8.9 million (95% cCI: 4.6–15.6 million), including 4.5 million (95% cCI: 2.6–7.6 million) in ACH and 4.4 million (95% cCI: 2.0–8.0 million) in LTCF; 3.8 million (95% cCI: 3.1–4.5 million) patients acquired an HAI each year in ACH. Antimicrobial resistance (AMR) to selected AMR markers was 31.6% in ACH and 28.0% in LTCF. Our study confirmed a high annual number of HAI in healthcare facilities in the EU/EEA and indicated that AMR in HAI in LTCF may have reached the same level as in ACH.