Recent improvements to the PROSITE database
Recent improvements to the PROSITE database
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DOI：
10.1093/nar/gkh044
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Bairoch, A
中科院分区：
文献类型：
--
作者：
Hulo, N;Sigrist, CJA;Bairoch, A
Prosite数据库由大量具有描述为模式或配置文件的生物学有意义的签名组成。每个签名都与文档有关，该文档提供了有关签名确定的蛋白质家族，域或功能部位的有用的生物学信息。 Prosite网页已重新设计，并且已经实施了几种工具，以帮助用户在自己的蛋白质中发现新的保守区域并可视化域的布置。我们还介绍了使用Prosite条目或用户的模式搜索PDB的设施，并在3D结构上可视化匹配的位置。最新版本的Prosite（2003年11月30日的发行版18.17）包含1676个条目。该数据库可在http://www.expasy.org/prosite/上访问。
The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE web page has been redesigned and several tools have been implemented to help the user discover new conserved regions in their own proteins and to visualize domain arrangements. We also introduced the facility to search PDB with a PROSITE entry or a user's pattern and visualize matched positions on 3D structures. The latest version of PROSITE (release 18.17 of November 30, 2003) contains 1676 entries. The database is accessible at http://www.expasy.org/prosite/.