Stress and sleep duration predict headache severity in chronic headache sufferers.
Stress and sleep duration predict headache severity in chronic headache sufferers.
复制标题
DOI：
10.1016/j.pain.2012.08.014
复制
发表时间：
2012-12
期刊：
影响因子：
7.4
通讯作者：
Penzien DB
中科院分区：
文献类型：
--
作者：
Houle TT;Butschek RA;Turner DP;Smitherman TA;Rains JC;Penzien DB
本研究的目的是评估慢性头痛患者的压力、睡眠时间和头痛之间的时间序列关系。长期以来，睡眠和压力一直被认为是发作性头痛(15天/月)的潜在触发因素，尽管在被诊断为慢性头痛(≥15天/月)的患者中，前瞻性的证据并不一致，而且缺乏前瞻性的证据。我们重新分析了对慢性偏头痛(n=33)和慢性紧张型头痛(n=22)患者进行的28天观察性研究的数据。患者完成每日压力清单，并使用每日睡眠/头痛日记记录头痛和睡眠变量。压力等级、前几个晚上的睡眠时间和头痛严重程度被用一系列线性混合模型建模，该模型带有随机效应，以考虑观察到的关联中的个体差异。模型用等值线图显示。连续两天的高压力或低睡眠强烈预示着头痛，而低压力或充足睡眠的两天则是保护性的。当压力或睡眠模式在一天中不同时，只有当前一天以高压力或睡眠不佳为特征时，头痛风险才会增加。正如预测的那样，当前两天同时出现高压力和低睡眠时，组合模型中的头痛活动最高，这表明这是一种相加效应。未来的研究需要扩大目前在慢性头痛患者中的发现，并开发个性化的模型，说明头痛触发因素的多个同时影响。
The objective of this study was to evaluate the time-series relationships between stress, sleep duration, and headache pain among patients with chronic headaches. Sleep and stress have long been recognized as potential triggers of episodic headache (< 15 headache days/month), though prospective evidence is inconsistent and absent in patients diagnosed with chronic headaches (≥ 15 days/month). We reanalyzed data from a 28-day observational study of chronic migraine (n = 33) and chronic tension-type headache (n = 22) sufferers. Patients completed the Daily Stress Inventory and recorded headache and sleep variables using a daily sleep/headache diary. Stress ratings, duration of previous nights' sleep, and headache severity were modeled using a series of linear mixed models with random effects to account for individual differences in observed associations. Models were displayed using contour plots. Two consecutive days of either high stress or low sleep were strongly predictive of headache, whereas two days of low stress or adequate sleep were protective. When patterns of stress or sleep were divergent across days, headache risk was increased only when the earlier day was characterized by high stress or poor sleep. As predicted, headache activity in the combined model was highest when high stress and low sleep occurred concurrently during the prior 2 days denoting an additive effect. Future research is needed to expand on current findings among chronic headache patients and to develop individualized models that account for multiple simultaneous influences of headache trigger factors.
登录
查看更多内容
影响因子：
9.9
作者：
Lipton, R. B.;Bigal, M. E.;Stewart, W. F.
通讯作者：
Stewart, W. F.
影响因子：
5
作者：
Boardman, HF;Thomas, E;Croft, PR
通讯作者：
Croft, PR
影响因子：
5
作者：
Calhoun, AH;Ford, S;Mann, ID
通讯作者：
Mann, ID
影响因子：
5
作者：
Chabriat, H;Danchot, J;Henry, P
通讯作者：
Henry, P
影响因子：
4.2
作者：
Gil, KM;Carson, JW;Orringer, E
通讯作者：
Orringer, E