Photoacoustic-guided focused ultrasound (PAFUSion) for identifying reflection artifacts in photoacoustic imaging
Photoacoustic-guided focused ultrasound (PAFUSion) for identifying reflection artifacts in photoacoustic imaging
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DOI：
10.1016/j.pacs.2015.09.001
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发表时间：
2015-12-01
期刊：
影响因子：
7.9
通讯作者：
Steenbergen, Wiendelt
中科院分区：
文献类型：
--
作者：
Singh, Mithun Kuniyil Ajith;Steenbergen, Wiendelt
声不均匀性及其反射伪影的影响是反射模式光声成像中的一个重要问题。皮肤和表面光吸收体对光的吸收会产生光声瞬态，光声瞬态穿过组织并被具有不同声阻抗的结构反射。这些反射光声信号，当重建时，可能出现在感兴趣的区域，这导致图像解释困难。我们提出了一种利用光声引导聚焦超声识别并消除光声图像中反射伪影的新方法[PAFUSion]。我们的方法使用聚焦超声脉冲来模拟光声源产生的波场，从而提供了一种识别临床光声和脉冲回波联合超声反射伪影的方法。仿真和仿真结果验证了该方法的有效性和有效性。结果表明，PAFUSion可以识别光声图像中的反射，从而设想了改善声不均匀组织的光声成像的潜力。(C) 2015年作者。Elsevier GmbH出版。这是一篇基于CC BY-NC-ND许可（http://creativecommons.org/licenses/by-nc-nd/4.0/）的开放获取文章。
Influence of acoustic inhomogeneities and resulting reflection artifacts is an important problem in reflection-mode photoacoustic imaging. Absorption of light by skin and superficial optical absorbers will generate photoacoustic transients, which traverse into the tissue and get reflected from structures having different acoustic impedance. These reflected photoacoustic signals, when reconstructed, may appear in the region of interest, which causes difficulties in image interpretation. We propose a novel method to identify and potentially eliminate reflection artifacts in photoacoustic images using photoacoustic-guided focused ultrasound [PAFUSion]. Our method uses focused ultrasound pulses to mimic the wave field produced by photoacoustic sources and thus provides a way to identify reflection artifacts in clinical combined photoacoustic and pulse-echo ultrasound. Simulation and phantom results are presented to demonstrate the validity and impact of this method. Results show that PAFUSion can identify reflections in photoacoustic images and thus envisages potential for improving photoacoustic imaging of acoustically inhomogeneous tissue. (C) 2015 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).