Surgery for focal epilepsy in the older patient
Surgery for focal epilepsy in the older patient
复制标题
老年患者局灶性癫痫手术
作者：
G. Cascino;F. Sharbrough;K. A. Hirschorn;W. Marsh
在梅奥诊所3年内接受顽固性部分癫痫手术治疗的237例患者中，有8例年龄在50岁或以上。所有患者都有致残性部分癫痫发作，持续数年，抗癫痫药物治疗无效。神经影像学鉴定癫痫性病变提示转诊手术治疗的三个病人。在这8名患者中，唯一与手术相关的临床显著发病率是一名接受左额叶皮质切除术的患者失语症的短暂加重。所有8例患者均有良好的癫痫发作结果，其中3例患者术后无癫痫发作。对于60岁或以上的难治性部分癫痫患者，癫痫手术可能是一种合适的替代疗法。
Eight of the 237 patients who received a surgical procedure for intractable partial epilepsy at the Mayo Clinic during a 3-year period were 50 years of age or older. All patients had disabling partial seizures of several years in duration that were refractory to anti epileptic drug medication. A neuroimaging-identified epileptogenic lesion prompted referral for surgical treatment in three patients. The only clinically significant morbidity associated with surgery in the eight patients was a transient exacerbation of an aphasia in a patient who underwent a left frontal corticectomy. All eight patients had a favorable seizure outcome, and three patients postoperatively are seizure free. Epilepsy surgery may be an appropriate alternate therapy for select patients in the sixth decade of life or older with medically refractory partial seizures.