Nicotine dependence, major depression, and anxiety in young adults.
Nicotine dependence, major depression, and anxiety in young adults.
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DOI：
10.1001/archpsyc.1991.01810360033005
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发表时间：
1991-12
影响因子：
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通讯作者：
N. Breslau;M. Kilbey;P. Andreski
中科院分区：
文献类型：
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作者：
N. Breslau;M. Kilbey;P. Andreski
为了确定按严重程度分类的尼古丁依赖是否与其他物质依赖、重度抑郁症和焦虑症相关，我们使用根据 DSM-III-R 修订的国家心理健康研究所诊断访谈表对底特律（密歇根州）地区的 1007 名年轻人进行了随机抽样研究。 DSM-III-R 尼古丁依赖标准的系统覆盖提供了前所未有的机会，可以将尼古丁依赖者与有吸烟史的较大人群区分开来，并检查尼古丁依赖者和非依赖吸烟者中精神疾病的患病率。尼古丁依赖的终生患病率为 20%。尼古丁依赖与酒精、大麻和可卡因依赖有关。控制其他物质依赖的影响后，尼古丁依赖者患重度抑郁症和焦虑症的几率较高。这些关联的强度因尼古丁依赖的严重程度而异。非依赖吸烟者对其他物质依赖的比例较高，但重度抑郁症或焦虑症的比例较高。
To determine whether nicotine dependence, classified by level of severity, was associated with other substance dependence, major depression, and anxiety disorders, we studied a random sample of 1007 young adults in the Detroit (Mich) area using the National Institute of Mental Health Diagnostic Interview Schedule, revised according to DSM-III-R. The systematic coverage of DSM-III-R criteria of nicotine dependence provides an unprecedented opportunity to separate persons with nicotine dependence from the larger class of persons with a history of smoking and to examine the prevalence of psychiatric disorders among persons with nicotine dependence and among nondependent smokers. The lifetime prevalence of nicotine dependence was 20%. Nicotine dependence was associated with alcohol, cannabis, and cocaine dependence. Controlling for the effects of other substance dependencies, persons with nicotine dependence had higher rates of major depression and anxiety disorders. The strength of these associations varied by level of severity of nicotine dependence. Nondependent smokers had higher rates of other substance dependencies, but not of major depression or anxiety disorders.