Characteristics of the banding patterns in non-Hodgkin and non-Burkitt lymphomas.
Characteristics of the banding patterns in non-Hodgkin and non-Burkitt lymphomas.
复制标题
非霍奇金淋巴瘤和非伯基特淋巴瘤的条带模式的特征。
作者：
J. Mark;C. Ekedahl;R. Dahlenfors
描述了在直接制备中研究的 6 种组织细胞淋巴瘤的条带模式。这些结果以及之前报道的 7 例病例的结果与文献中另外 32 例非霍奇金和非伯基特淋巴瘤的数据（通常不完整）一起进行了调查。这些类型的淋巴瘤具有以下特征：（1）14号最常受影响，通常是由于涉及其长臂的结构偏差，尤其是q32带；这通常会导致 14q + 标记的形成，在 45 个病例中的 17 个病例中发现； 14 号的额外材料显示出不一致的推导，与伯基特淋巴瘤相比存在差异。 (2) 涉及频率次之的是第3、7、8、11号； 3 号和 11 号的结构偏差占主导地位，并且出现了一些重复出现的标记类型； 7号和8号主要受到数值偏差的影响，通常是7号上涨，8号下跌。 (3)结构偏差经常影响1、6、9和13号，并且出现与6和13号相关的重复标记类型。 (4) 着丝粒和浅染区域优先受断点影响。
The banding patterns in 6 histiocytic lymphomas, studied in direct preparations, are described. These results, and those in 7 cases – reported earlier, are surveyed together with data, often incomplete, from 32 further non-Hodgkin and non-Burkitt lymphomas in the literature. The following features characterized these types of lymphomas: (1) No. 14 was most commonly affected, usually by structural deviations involving its long arm, preferentially band q32; this, as a rule, resulted in formation of 14q + markers, found in 17 of the 45 cases; the extra material on No. 14 showed inconsistent derivation, a difference in comparison with Burkitt lymphomas. (2) Nos. 3, 7, 8 and 11 were next in frequency of involvement; structural deviations predominated for Nos. 3 and 11, and some recurrent marker types were seen; Nos. 7 and 8 were mostly affected by numerical deviations, usually gains for No. 7 and losses for No. 8. (3) Structural deviations often affected Nos. 1, 6, 9 and 13 and recurrent marker types related to Nos. 6 and 13 were seen. (4) The centromeric and the light-staining regions were preferentially affected by the breakpoints.