Behavioral Oscillation in Priming: Competing Perceptual Predictions Conveyed in Alternating Theta-Band Rhythms
Behavioral Oscillation in Priming: Competing Perceptual Predictions Conveyed in Alternating Theta-Band Rhythms
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DOI：
10.1523/jneurosci.4294-14.2015
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发表时间：
2015-02-11
影响因子：
5.3
通讯作者：
Luo, Huan
中科院分区：
文献类型：
--
作者：
Huang, Yan;Chen, Lin;Luo, Huan
大脑不断地对即将到来的刺激产生感知预测，以有效地引导感知。大量的研究表明，知觉预测调节感觉活动取决于实际输入是否与一个特定的预测一致。然而，在现实生活中，可能会同时存在多个甚至相互冲突的预测进行测试，这需要多预测协调过程。在很大程度上，人们仍然不知道如何传达和协调多种假设，以指导每时每刻的感知。基于最近的研究结果揭示，多个位置交替采样在不同阶段的注意节奏，我们假设，这种振荡为基础的时间组织机制也可能是多预测协调过程的基础。为了解决这个问题，我们使用完善的启动范式结合时间分辨行为的方法来研究人类受试者的多预测协调过程的精细时间动态。我们首先复制了经典启动效应的缓慢发展趋势的启动时间过程。第二，在删除典型的启动模式，我们揭示了一个新的θ波段（类似4赫兹）的振荡成分在启动行为数据，无论是否总理被掩盖。第三，我们发现，这些θ波段启动振荡触发的全等和不全等素数是在一个相位的关系。这些发现表明，知觉预测返回到低感觉区不连续，但在θ波段节奏（每200-300毫秒），并在时间上动态协调的多个预测被传达在不同阶段的θ波段振荡，以实现分离，但时间上有组织的神经表征。
The brain constantly creates perceptual predictions about forthcoming stimuli to guide perception efficiently. Abundant studies have demonstrated that perceptual predictions modulate sensory activities depending on whether the actual inputs are consistent with one particular prediction. In real-life contexts, however, multiple and even conflicting predictions might concurrently exist to be tested, requiring a multiprediction coordination process. It remains largely unknown how multiple hypotheses are conveyed and harmonized to guide moment-by-moment perception. Based on recent findings revealing that multiple locations are sampled alternatively in various phase of attentional rhythms, we hypothesize that this oscillation-based temporal organization mechanism may also underlie the multiprediction coordination process. To address the issue, we used well established priming paradigms in combination with a time-resolved behavioral approach to investigate the fine temporal dynamics of the multiprediction harmonization course in human subjects. We first replicate classical priming effects in slowly developing trends of priming time courses. Second, after removing the typical priming patterns, we reveal a new theta-band (similar to 4 Hz) oscillatory component in the priming behavioral data regardless of whether the prime was masked. Third, we show that these theta-band priming oscillations triggered by congruent and incongruent primes are in an out-of-phase relationship. These findings suggest that perceptual predictions return to low-sensory areas not continuously but recurrently in a theta-band rhythm (every 200-300 ms) and that multiple predictions are dynamically coordinated in time by being conveyed in different phases of the theta-band oscillations to achieve dissociated but temporally organized neural representations.