Quantifying head motion associated with motor tasks used in fMRI
Quantifying head motion associated with motor tasks used in fMRI
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DOI：
10.1006/nimg.2001.0829
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发表时间：
2001-08-01
期刊：
影响因子：
5.7
通讯作者：
Graham, SJ
中科院分区：
文献类型：
--
作者：
Seto, E;Sela, G;Graham, SJ
在功能磁共振成像 (fMRI) 研究中，较长的实验时间和与大脑激活相关的较小的强度变化经常导致由于头部运动而产生图像伪影。通常将通过约束、快速成像和回顾性图像配准来最小化和校正头部运动的方法结合起来，但并不能完全解决问题，特别是对于特定的患者群体。作为优化未来头枕设计和改进运动矫正技术的第一步，借助 AIR 模拟器和高精度位置跟踪系统，研究了中风受试者组、年龄匹配对照组和年轻人的头部运动特征。在涉及手或脚的运动任务期间记录位置测量值。根据方差分析计算，头部运动很大程度上取决于受试者组，而较少取决于任务条件（P < 0.05）。与同龄对照组相比，中风受试者表现出的头部运动大约是其两倍，而后者的头部运动大约是年轻人的两倍。此外，中风受试者在所有任务中的头部运动范围约为 2±1 毫米，运动主要发生为上下方向的平移和俯仰旋转（点头）。这些结果提出了关于功能磁共振成像运动实验设计的一些建议，并表明需要改进运动校正策略来全面检查此类患者群体。 (C) 2001 年学术出版社。
In functional magnetic resonance imaging (fMRI) studies, long experiment times and small intensity changes associated with brain activation frequently lead to image artifacts due to head motion. Methods to minimize and correct for head motion by restraint, fast imaging, and retrospective image registration are typically combined but do not completely solve the problem, particularly for specific patient populations. As an initial step toward optimizing future designs of head restraints and improving motion correction techniques, the head motion characteristics of groups of stroke subjects, age-matched controls, and young adults were investigated with the aid of an AIR simulator and a highly accurate position tracking system. Position measurements were recorded during motor tasks involving either the hand or the foot. Head motion was strongly dependent on the subject group and less upon the task conditions based on ANOVA calculations (P < 0.05). The stroke subjects exhibited approximately twice the head motion compared to that of age-matched controls, and the latter's head motion was about twice that of young adults. Moreover, the range of head motion in stroke subjects over all tasks was approximately 2 1 mm, with the motion occurring predominantly as translation in the superior-inferior direction and pitch rotation (nodding). These results lead to several recommendations on the design of fMRI motor experiments and suggest that improved motion correction strategies are required to examine such patient populations comprehensively. (C) 2001 Academic Press.