The Rate of Absorption of Ragweed Pollen Material from the Nose

The Rate of Absorption of Ragweed Pollen Material from the Nose
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豚草花粉物质从鼻子的吸收率

DOI:
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发表时间:
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影响因子:
4.4
通讯作者:
J. Rudolph
J. Rudolph
中科院分区:
医学2区
文献类型:
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作者:
Milton B. Cohen;E. E. Ecker;J. Breitbart;J. Rudolph

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使用对豚草高度敏感的患者的血清对 50 名非特应性受试者和 12 名患有哮喘、花粉热或血管舒缩性鼻炎的患者进行了 Prausnitz-Küstner 反应,其中 9 名患者通过划痕试验出现皮肤反应。患者对豚草并不自然敏感。二十四小时后,将花粉吹入非特应性和特应性受试者的两个鼻孔中,并观察注射部位是否出现发红和风团形成。非特应性受试者的吸收时间从十四分钟到三十一分钟不等,而9名出现皮肤反应的敏感受试者的吸收时间则表现出明显的延迟,从四十七分钟到两小时后没有反应。另外三名皮肤测试呈阴性的人的反应与非过敏者一样。
A Prausnitz-Küstner reaction was performed with the serum of a patient highly sensitive to ragweed on 50 non-atopic subjects and 12 patients with asthma, hay fever, or vasomotor rhinitis, nine of whom gave skin reactions by scratch tests. The patients were not naturally sensitive to ragweed. Twenty-four hours later the pollen was blown into both nostrils of the non-atopic and atopic subjects and the sites of injections observed for the appearance of redness and wheal formation. The absorption time of the non-atopic subjects varied from fourteen minutes to thirty-one minutes, while that of the 9 sensitive subjects giving a skin reaction showed a marked delay, ranging from forty-seven minutes to no reaction after two hours. The other three with negative skin tests reacted like the non-atopics.