Fabrication of uniform magnetic nanocomposite spheres with a magnetic core/mesoporous silica shell structure

Fabrication of uniform magnetic nanocomposite spheres with a magnetic core/mesoporous silica shell structure
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DOI:
10.1021/ja051113r
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发表时间:
2005-06-29
影响因子:
15
通讯作者:
Shi, JL
Shi, JL
中科院分区:
化学1区
文献类型:
--
作者:
Zhao, WR;Gu, JL;Shi, JL

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制备了一种新型的磁性核/介孔二氧化硅壳纳米球,其粒径均匀,270 nm合成。内磁核赋予了整个纳米粒子的磁性,而外介孔二氧化硅壳显示出足够高的表面积和孔体积。该材料有望应用于靶向给药和多相分离领域。作为一个典型的例子,布洛芬的存储和释放到和从介孔二氧化硅壳的孔道,被证明。
A novel kind of magnetic core/mesoporous silica shell nanospheres with a uniform particle diameter of ca. 270 nm was synthesized. The inner magnetic core endues the whole nanoparticle with magnetic properties, while the outer mesoporous silica shell shows high enough surface area and pore volume. The synthesized material is expected to be applied to targeted drug delivery and multiphase separation. The storage and release of ibuprofen into and from the pore channels of the mesoporous silica shell, as a typical example, are demonstrated.