Diagnostic Accuracy of Myocardial Hypoenhancement on Multidetector Computed Tomography in Identifying Myocardial Infarction in Patients Admitted With Acute Chest Pain Syndrome

Diagnostic Accuracy of Myocardial Hypoenhancement on Multidetector Computed Tomography in Identifying Myocardial Infarction in Patients Admitted With Acute Chest Pain Syndrome
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多排计算机断层扫描心肌低增强对急性胸痛综合征患者心肌梗死的诊断准确性

DOI:
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发表时间:
2007
影响因子:
1.3
通讯作者:
R. Beyar
R. Beyar
中科院分区:
医学4区
文献类型:
--
作者:
J. Lessick;E. Ghersin;R. Dragu;D. Litmanovich;D. Mutlak;S. Rispler;Y. Agmon;A. Engel;R. Beyar

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目的:使用多探测器计算机断层扫描(MDCT)评估因急性胸痛综合征入院的患者中心肌低增强(MH)的患病率和诊断准确性。方法:69例患者接受了MDCT、冠状动脉造影和超声心动图检查。使用标准化的分析方案,左心室短轴重构的存在,大小和密度的MH在16个心肌节段进行了评价。这些与心肌梗死(MI)的存在和位置、局部心肌功能障碍和冠状动脉疾病相关。结果:急性心肌梗死(27/35)、痊愈心肌梗死(6/14)、不稳定型心绞痛(3/9)、不典型胸痛(0/11)患者心肌呈低强化。MH诊断MI的敏感性、特异性、阳性预测值和阴性预测值分别为67%、85%、92%和52%。结论:急性胸痛患者MDCT上MH的存在具有较高的阳性预测值和特异性,但使用本研究中提出的严格标准,对于急性或已愈合MI的存在仅具有中等敏感性。
Objective: To evaluate prevalence and diagnostic accuracy of myocardial hypoenhancement (MH) using multidetector computed tomography (MDCT) in patients admitted for acute chest pain syndromes. Methods: Sixty-nine patients underwent first-pass MDCT, coronary angiography, and echocardiography. Using a standardized analysis protocol, left ventricular short-axis reformations were evaluated for presence, size, and density of MH in 16 myocardial segments. These were correlated with the presence and location of myocardial infarction (MI), regional myocardial dysfunction, and coronary artery disease. Results: Myocardial hypoenhancement was found in acute MI (27/35), healed MI (6/14), unstable angina (3/9), and atypical chest pain (0/11). Sensitivity, specificity, and positive and negative predictive values of MH for diagnosing any MI were 67%, 85%, 92% and 52%, respectively. Conclusions: The presence of MH on MDCT in acute chest pain patients has high positive predictive value and specificity but only moderate sensitivity for presence of acute or healed MI using the strict criteria proposed in this study.
DOI: 10.1161/01.cir.97.8.765
发表时间: 1998-03-03
期刊: CIRCULATION
影响因子: 37.8
作者:
Wu, KC;Zerhouni, EA;Lima, JAC
通讯作者: Lima, JAC
DOI: 10.1016/s0735-1097(02)02962-5
发表时间: 2003-03-05
影响因子: 24
作者:
Balcells, E;Powers, ER;Lindner, JR
通讯作者: Lindner, JR
DOI: 10.1161/01.cir.92.5.1117
发表时间: 1995-09-01
期刊: CIRCULATION
影响因子: 37.8
作者:
LIMA, JAC;JUDD, RM;ZERHOUNI, EA
通讯作者: ZERHOUNI, EA