Vitamin D Level in Summer and Winter Related to Measured UVR Exposure and Behavior
Vitamin D Level in Summer and Winter Related to Measured UVR Exposure and Behavior
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DOI：
10.1111/j.1751-1097.2009.00612.x
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发表时间：
2009-11-01
影响因子：
3.3
通讯作者：
Wulf, Hans Christian
中科院分区：
文献类型：
--
作者：
Thieden, Elisabeth;Philipsen, Peter A.;Wulf, Hans Christian
在25名健康成年志愿者的开放性研究中，研究了夏季紫外线照射对夏末和冬季血清25-羟基维生素D（25（OH）D）的影响。在一个夏季，个人，电子手表UVR剂量计和阳光照射日记的UVR暴露剂量在标准红斑剂量（SED）进行了连续监测。9月测量了组成性和兼性皮肤色素沉着。在9月和2月测量25（OH）D，9月的平均值为82 nmol/L +/- 25（平均值+/- SD），2月为56 nmol/L +/- 19（平均值+/- SD）。在平均121天内测量的接受累积UVR剂量为156 SED +/- 159（平均值+/- SD）。以下UVR暴露参数分别与9月和2月的25（OH）D相关：（1）累积UVR剂量（r = 0.53; P < 0.01），（r = 0.43; P = 0.03）;（2）剂量计监测UVR测量的平均每日小时数（r = 0.64，P = 0.001）和（3）“上身日晒”天数（4）兼性色素沉着（r = 0.47; P <0.02）和（r = 0.7; P <0.001）;（5）组成性色素沉着（r = 0.06，n.s.）r = 0.43，P = 0.03。无论是“日光浴”还是“涂抹防晒霜”的天数都与25（OH）D无关。冬季25（OH）D的下降取决于入口值。
The influence of the summer UVR exposure on serum-25-hydroxyvitamin D (25(OH) D) in late summer and winter was investigated in an open study on 25 healthy, adult volunteers. The UVR exposure dose in standard erythema dose (SED) was monitored continuously during a summer season with personal, electronic wristwatch UVR dosimeters and sun exposure diaries. Constitutive and facultative skin pigmentation was measured in September. 25(OH) D was measured in September and February and was in mean 82 nmol/L +/- 25 (mean +/- SD) in September and 56 nmol/L +/- 19 (mean +/- SD) in February. The received cumulative UVR dose measured during a mean of 121 days was 156 SED +/- 159 (mean +/- SD). The following UVR exposure parameters correlated with 25(OH) D in September and February, respectively: (1) The cumulative UVR dose (r = 0.53; P < 0.01) and (r = 0.43; P = 0.03); (2) Mean daily hours with UVR measurements monitored by the dosimeter (r = 0.64, P = 0.001) and (r = 0.53; P = 0.007); (3) Days "with sun-exposed upper body" (r = 0.58, P = 0.003) and (r = 0.50; P = 0.01); (4) Facultative pigmentation (r = 0.47; P < 0.02) and (r = 0.7; P < 0.001); (5) Constitutive pigmentation (r = 0.06, n.s.) and (r = 0.43, P = 0.03). Neither days "sunbathing" nor days with "sunscreen applied" correlated with 25(OH)D. The fall in 25(OH)D during winter was dependent on the entry value.