The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with focal plane array detector, X-ray photoelectron microscopy and HaCaT cells
The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with focal plane array detector, X-ray photoelectron microscopy and HaCaT cells
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DOI：
10.1111/ics.12360
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发表时间：
2017-04-01
影响因子：
2.3
通讯作者：
Lee, J. H.
中科院分区：
文献类型：
--
作者：
Jung, I. K.;Park, S. C.;Lee, J. H.
ObjectiveCoacervates are inevitably formed on scalp on using hair washing products. Our goal was to analyse the coacervates in detail to identify the part responsible for scalp stimulation.MethodsShampoo that increases coacervate formation was applied to in vitro skin and was washed. The residue was then analysed using Fourier transform infrared spectroscopy-focal plane array (FTIR-FPA) and X-ray photoelectron microscopy (XPS). And HaCaT cells were used for irritant test of coacervate.ResultsThrough this research, it was confirmed that the coacervate was a macromolecule structurally similar to a cationic polymer and contains an anionic surfactant. Its anionic surfactant was structurally semi-stable so that it released onto scalp when it absorbs moisture.ConclusionCoacervate releases sulphate bonding into the matrix when it is exposed to water. Thus, the scalp stimulation would be expected.ResumeObjectifDes coacervats sont inevitablement formes sur le cuir chevelu lors de l'utilisation de produits de lavage des cheveux. Notre objectif etait d'analyser les coacervats en detail pour identifier la partie responsable de l'irritation du cuir chevelu.MethodesUn shampoo qui augmente la formation de coacervats a ete applique sur la peau in vitro et a ete lave. Le residu a ensuite ete analyse a l'aide de la spectroscopie infrarouge a transformee de Fourier au plan focal (FTIR-FPA), et de la microscopie a photoelectrons X (XPS). Les cellules HaCaT ont ete utilisees pour le test d'irritation du coacervat.ResultatsGrace a cette recherche, il a ete confirme que le coacervat est une macromolecule structurellement similaire a un polymere cationique et contient un agent tensio-actif anionique. Son tensioactif anionique etait structurellement semi-stable de sorte qu'il relargue sur le cuir chevelu quand il absorbe de l'humidite.ConclusionLe coacervat libere la liaison de sulfate dans la matrice quand il est expose a l'eau. Ainsi, l'irritation du cuir chevelu est attendue.
