Delayed Patch-Test Reading After 5 Days: An Update From the Mayo Clinic Contact Dermatitis Group
Delayed Patch-Test Reading After 5 Days: An Update From the Mayo Clinic Contact Dermatitis Group
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DOI：
10.1097/der.0000000000000297
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发表时间：
2017-07-01
期刊：
影响因子：
5.2
通讯作者：
Davis, Mark D. P.
中科院分区：
文献类型：
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作者：
Chaudhry, Hafsa M.;Drage, Lisa A.;Davis, Mark D. P.
背景：第5天后的斑贴试验读数以前用于确定对金属和局部抗生素的延迟反应。目的：本研究的目的是确定晚期读数（超过5天）最有价值的过敏原，并将我们的结果与我们之前关于延迟斑贴试验读数的研究进行比较。方法：对2007年1月1日至2013年12月31日期间接受金属和皮质类固醇系列贴片试验的298例患者进行回顾性研究。在第3天和第5天进行局部测试读数，在第7天和第14天之间至少进行一次。每次阅读时都检查所有的反应。结论：这些结果与我们之前的发现一致，即第7天之后的额外读数对于识别对金属（金，钴，铍，钯），特定防腐剂（十二烷基没食子酸酯，蜂胶）和局部抗生素新霉素的反应特别有用。在本队列中未见杆菌肽、对苯二胺和局部皮质类固醇的新延迟反应。
Background: Patch-test readings after day 5 have previously been used to identify delayed reactions to metals and topical antibiotics.Objective: The aims of this study were to identify allergens for which late readings (beyond day 5) would be most valuable and to compare our results with our previous study on delayed patch-test readings.Methods: This was a retrospective study of 298 patients who underwent metal and corticosteroid series patch testing from January 1, 2007, through December 31, 2013. Patch-test readings were conducted on days 3 and 5 and at least once sometime between days 7 and 14. All reactions were examined at each reading.Conclusions: These results were concordant with our previous findings that additional readings after day 7 are particularly useful for identifying reactions to metals (gold, cobalt, beryllium, palladium), specific preservatives (dodecyl gallate, propolis), and the topical antibiotic neomycin. New delayed reactions to bacitracin, p-phenylenediamine, and topical corticosteroids were not seen in this cohort.