Feasibility of the use of the Active Breathing Co ordinator™ (ABC) in patients receiving radical radiotherapy for non-small cell lung cancer (NSCLC)
Feasibility of the use of the Active Breathing Co ordinator™ (ABC) in patients receiving radical radiotherapy for non-small cell lung cancer (NSCLC)
复制标题
DOI：
10.1016/j.radonc.2009.09.012
复制
发表时间：
2009-12-01
影响因子：
5.7
通讯作者：
Brada, Michael
中科院分区：
文献类型：
--
作者：
McNair, Helen A.;Brock, Juliet;Brada, Michael
简介：克服用放射疗法治疗的患者中的肺肿瘤运动的问题的一种方法是用主动呼吸控制（ABC）装置限制肿瘤运动。本研究评价了ABC在接受根治性放疗的非小细胞肺癌患者中应用的可行性。方法：18例患者，中位（范围）年龄66（44- 82）岁，同意参加本研究。进行培训课程以确定患者的屏气水平和屏气时间使用ABC设备获取三次计划扫描通过比较计划扫描前测量的肺体积和ABC记录的体积来评估屏气的可重复性患者接受治疗3场共面束排列和治疗时间（患者在床上和离开床）和记录的屏气次数。通过每周问卷评估装置的耐受性。结果：17/18例患者使用ABC完成了32次放疗，所有患者均耐受最大屏气时间>15 s。平均（SD）患者训练时间为13 8（4 8）min，没有患者发现ABC非常不舒服。每次训练需要6 - 13次屏气，每次10-14秒。平均治疗时间为15.8分钟（5.8分钟），屏气量在治疗过程中和两种ABC装置之间具有重复性。结论：ABC用于NSCLC根治性放疗是可行的。无法预测患者屏住呼吸的能力。建议在开始治疗前进行最小耐受屏气15秒。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。放射治疗和肿瘤学93（2009）424-429
Introduction: One method to overcome the problem of lung tumour movement in patients treated with radiotherapy is to restrict tumour motion with an active breathing control (ABC) device. This study evaluated the feasibility of using ABC in patients receiving radical radiotherapy for non-small cell lung cancer.Methods, Eighteen patients, median (range) age of 66 (44- 82) years, consented to the study. A training session was conducted to establish the patient's breath hold level and breath hold time Three planning scans were acquired using the ABC device Reproducibility of breath hold was assessed by comparing lung volumes measured front the planning scans and the volume recorded by ABC Patients were treated with a 3-field coplanar beam arrangement and treatment time (patient on and off the bed) and number of breath holds recorded The tolerability of the device was assessed by weekly questionnaire. Quality assurance was performed on the two ABC devices used.Results: 17/18 patients completed 32 fractions of radiotherapy using ABC All patients tolerated a maximum breath hold tinge >15 s. The mean (SD) patient training time was 13 8 (4 8) min and no patient found the ABC very uncomfortable. Six to thirteen breath holds of 10-14 s were required per session. The mean treatment tinge was 15.8 ruin (5.8 min) The breath hold volumes were reproducible during treatment and also between the two ABC devicesConclusion: The use of ABC in patients receiving radical radiotherapy for NSCLC is feasible. It was not possible to predict a patient's ability to hold breath. A minimum tolerated breath hold tinge of 15 s is recommended prior to commencing treatment. (C) 2009 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 93 (2009) 424-429