QUANTITATIVE MORPHOLOGY OF ANISOTROPIC TRABECULAR BONE
QUANTITATIVE MORPHOLOGY OF ANISOTROPIC TRABECULAR BONE
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DOI：
10.1111/j.1365-2818.1974.tb03878.x
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发表时间：
1974-01-01
影响因子：
2
通讯作者：
WHITEHOUSE, WJ
中科院分区：
文献类型：
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作者：
WHITEHOUSE, WJ
使用Quantimet图像分析计算机对小梁骨切片的低放大倍率扫描电子显微照片的少量描迹进行尺寸测量，以定量表达局部骨图案的特性。测量骨与骨髓之间的界面边界轮廓的正交投影长度作为投影方向的函数，这表明大多数图案具有明显的各向异性。提出了计算公式根据骨骼的平均面积和边界轮廓长度，显示在切片表面上的小梁带的平均宽度。由于该公式的有效性在理论上并不明显，因此将结果与直接实验测量结果进行了比较，结果发现非常吻合。骨和骨髓空间中的平均截距长度已计算为横截面方向的函数。人们发现这些长度的极坐标图具有椭圆形，其精确度出乎意料。这使得可以用单个数字来表达图案各向同性的偏离，例如通过椭圆轴的比率。简要讨论了这些实验中使用的方法的基本局限性，特别是通过此类实验不可能找到表面图案的精确对称性。
Dimensional measurements have been made on a small number of tracings of low magnification scanning electron micrographs of trabecular bone sections, using the Quantimet Image Analysing Computer, with a view to expressing the properties of the local bone pattern in a quantitative manner.Measurements of the orthogonally projected length of the boundary profile of the interface between bone and marrow were made as a function of the direction of projection, and these showed that the majority of the patterns were distinctly anisotropic.A formula is proposed for calculating the mean widths of the trabecular bands as they appear on the surfaces of the sections, from the mean area of bone and the boundary profile length. As the validity of this formula is not theoretically evident, the results have been compared with direct experimental measurements, and found to agree very well.The mean intercept lengths in the bone and in the marrow spaces have been calculated as a function of direction across the section. The polar diagrams of these lengths are found to have the shapes of ellipses, to an unexpected degree of accuracy. This makes it possible to express the departure from isotropy of the pattern by a single number, for instance by the ratio of the axes of the ellipse.The essential limitations of the methods used in these experiments are briefly discussed, in particular the impossibility of finding the exact symmetry properties of the surface patterns by experiments of this type.