Electrochemical simultaneous determination of hydroquinone and p-nitrophenol based on host–guest molecular recognition capability of dual β-cyclodextrin functionalized Au@graphene nanohybrids
Electrochemical simultaneous determination of hydroquinone and p-nitrophenol based on host–guest molecular recognition capability of dual β-cyclodextrin functionalized Au@graphene nanohybrids
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DOI：
10.1016/j.snb.2014.10.083
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发表时间：
2015-02
影响因子：
8.4
通讯作者：
Long Yang;H Zhao;Yucong Li;Can-Peng Li
中科院分区：
文献类型：
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作者：
Long Yang;H Zhao;Yucong Li;Can-Peng Li
环糊精(CDS)具有优异的主客体分子识别能力，被广泛应用于纳米级的电化学器件中。在这项研究中，使用绿色方法在温和的条件下不使用任何额外的表面活性剂或还原剂，将均匀、单分散的4.5纳米金纳米颗粒(Au NPs)锚定在羧基石墨烯纳米片(CGS)上。将β-Cd(SH/NH_2-β-Cd)功能化的Au@CGS(β-Cd-Au@CGS)通过硫醇和羧基的偶联反应成功地制备了β-CD纳米杂化材料。用β-Cd-Au@CGS纳米杂化修饰玻碳电极同时测定对苯二酚和对硝基苯酚。在最佳条件下，采用差示脉冲伏安法同时测定HQ和PNP的浓度范围为0.0 1~2 0 0 0μM。HQ和PNP的定量下限均为0.01gμM。β-Cd-Au@CGS-纳米杂化电极对HQ和PNP的检出限分别为6.5nM和3.8nM。干扰研究结果表明，β-Cd-Au@CgS-纳米杂化电极对HQ和PNP的测定没有干扰，说明该电极具有较高的选择性。电化学传感器的低检测限和高选择性是由于β-Cd-Au@CgS纳米杂化材料具有高比表面积、良好的导电性和高的主客体分子识别能力。
Cyclodextrins (CDs) are extensively used in nanoscale electrochemical devices because of their outstanding host–guest molecular recognition capability. In this study, uniform, monodispersed 4.5 nm gold nanoparticles (Au NPs) were anchored onto carboxylic graphene nanosheets (CGS) using a green approach performed under mild conditions and without using any additional surfactant or reductant. A dual β-CD (SH/NH2-β-CD)-functionalized Au@CGS (β-CD–Au@CGS) nanohybrid was successfully fabricated by subsequent conjugation of β-CD with the aid of thiol and carboxyl groups. Simultaneous electrochemical determination of hydroquinone (HQ) andp-nitrophenol (PNP) using a β-CD–Au@CGS nanohybrid-modified glassy carbon electrode was conducted. Differential pulse voltammetry was used to simultaneously quantify HQ and PNP within the concentration range of 0.01–200 μM under optimal conditions. The limits of quantification for both HQ and PNP were 0.01 μM. The detection limits (S/N = 3) of the β-CD–Au@CGS-nanohybrid electrode for HQ and PNP were 6.5 and 3.8 nM, respectively. Interference study results demonstrated that several similar aromatic compounds did not interfere during the determination of HQ and PNP, indicating the high selectivity of the β-CD–Au@CGS-nanohybrid electrode. The low detection limit and high selectivity of the proposed electrochemical sensor were caused by the high surface area, the excellent conductivity, and the high host–guest molecular recognition capability of the β-CD–Au@CGS nanohybrids.