Cluster synchronization and spatio-temporal dynamics in networks of oscillatory and excitable Luo-Rudy cells
Cluster synchronization and spatio-temporal dynamics in networks of oscillatory and excitable Luo-Rudy cells
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DOI：
10.1063/1.2437581
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发表时间：
2007-03-01
期刊：
影响因子：
2.9
通讯作者：
Kurths, J.
中科院分区：
文献类型：
--
作者：
Kanakov, O. I.;Osipov, G. V.;Kurths, J.
我们研究集体现象在非均匀的心脏细胞培养模型，包括一维和二维晶格的振荡细胞和振荡和兴奋细胞的混合物。单个细胞的动力学模型采用修正的Luo-Rudy模型。我们专注于从非相干行为的过渡到全球同步通过集群同步制度的耦合强度的增加。这些制度的特点是定性的时空图和定量的本地频率和集群大小的分布依赖于耦合强度的配置文件。我们描述了在这个过渡过程中产生的时空模式，包括起搏器，螺旋波，和复杂的不规则活动。(c)2007年，美国物理学会。
We study collective phenomena in nonhomogeneous cardiac cell culture models, including one- and two-dimensional lattices of oscillatory cells and mixtures of oscillatory and excitable cells. Individual cell dynamics is described by a modified Luo-Rudy model with depolarizing current. We focus on the transition from incoherent behavior to global synchronization via cluster synchronization regimes as coupling strength is increased. These regimes are characterized qualitatively by space-time plots and quantitatively by profiles of local frequencies and distributions of cluster sizes in dependence upon coupling strength. We describe spatio-temporal patterns arising during this transition, including pacemakers, spiral waves, and complicated irregular activity. (c) 2007 American Institute of Physics.