Conformations of linear DNA
Conformations of linear DNA
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DOI：
10.1103/physreve.55.7364
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发表时间：
1997-06-01
影响因子：
2.4
通讯作者：
Ostlund, S
中科院分区：
文献类型：
--
作者：
Fain, B;Rudnick, J;Ostlund, S
我们检查一个模型的构象为欠缠绕和过缠绕的DNA。分子被表示为一个圆柱形对称的弹性弦，受到拉伸力和相应的连接数规范的约束。我们推导了描述曲线的欧拉角与拓扑连接数之间的基本关系。得到了分子在无限长极限下的空间构型的解析表达式。在给定的一组物理条件下，一个独特的配置使能量最小化。考虑热波动的弹性模型与实验结果非常吻合。
We examine the conformations of a model for underwound and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding tb a specification of the link number. We derive a fundamental relation between the Euler angles that describe the curve and the topological linking number. Analytical expressions for the spatial configurations of the molecule in the infinite-length limit are obtained. A unique configuration minimizes the energy for a given set of physical conditions. An elastic model incorporating thermal fluctuations provides excellent agreement with experimental results on the plectonemic transition.