STRUCTURE OF THE ARABIDOPSIS RPM1 GENE ENABLING DUAL-SPECIFICITY DISEASE RESISTANCE
STRUCTURE OF THE ARABIDOPSIS RPM1 GENE ENABLING DUAL-SPECIFICITY DISEASE RESISTANCE
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DOI：
10.1126/science.7638602
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发表时间：
1995-08-11
期刊：
影响因子：
56.9
通讯作者：
DANGL, JL
中科院分区：
文献类型：
--
作者：
GRANT, MR;GODIARD, L;DANGL, JL
植物可以通过抗病基因(R)的作用来识别病原体，这些抗病基因表达了独特的相应的无毒基因（avr），赋予病原体抗性。这种基因对基因特异性的分子基础尚不清楚。拟南芥RPM1基因对表达两种不相关的丁香假单胞菌avr基因之一的病原体具有双重特异性。尽管具有这种功能，RPM1编码的蛋白质与最近描述的单特异性R基因具有相同的分子特征。令人惊讶的是，在自然发生的易受疾病影响的拟南芥中缺乏RPM1。
Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.