PERNICIOUS-ANEMIA AS A RISK FACTOR FOR OSTEOPOROSIS
PERNICIOUS-ANEMIA AS A RISK FACTOR FOR OSTEOPOROSIS
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DOI：
10.1042/cs0820681
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发表时间：
1992-06-01
期刊：
影响因子：
6
通讯作者：
RIGGS, BL
中科院分区：
文献类型：
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作者：
EASTELL, R;VIEIRA, NE;RIGGS, BL
1. 如果胃酸是吸收膳食钙所必需的，则恶性贫血中出现的胃酸分泌完全缺失可能会导致骨质流失。为了调查这一点，我们测量了 21 名患有恶性贫血的绝经后妇女（年龄 51-76 岁）和 24 名正常绝经后妇女（年龄 51-79 岁）的钙吸收和骨密度。2．与正常女性相比，患有恶性贫血的女性腰椎骨密度降低了16%（P
1. If gastric acid is necessary for the absorption of dietary calcium, the total absence of gastric acid secretion that occurs in pernicious anaemia could result in bone loss. To investigate this, we measured calcium absorption and bone density in 21 postmenopausal women (ages 51-76 years) with pernicious anaemia and in 24 normal postmenopausal women (ages 51-79 years).2. Relative to the normal women, in the women with pernicious anaemia the bone mineral density of the lumbar spine was decreased by 16% (P