Predictors of postnatal depression in an urban South African cohort
Predictors of postnatal depression in an urban South African cohort
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DOI：
10.1016/j.jad.2008.05.007
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发表时间：
2009-03-01
影响因子：
6.6
通讯作者：
Norris, Shane A.
中科院分区：
文献类型：
--
作者：
Ramchandani, Paul G.;Richter, Linda M.;Norris, Shane A.
背景：产后抑郁症对孕产妇和儿童健康都有重大影响。在发展中国家，很少有研究确定有产后抑郁风险的妇女。本研究的目的是探讨发生产后抑郁症的危险因素在城市南非women.Method：一个大型的前瞻性人群队列研究确定了产前产后抑郁症的危险因素在索韦托，约翰内斯堡，南非。1035名妇女在产前进行了访谈，随后在产后完成了Pitt抑郁问卷调查。结果：170/1035（16.4%）的妇女是可能的情况下，产后抑郁症。产后抑郁症最强的独立预测因子是暴露于极端的社会压力（目击暴力犯罪/有被杀的危险）（调整的比值比2.468（95%置信区间1.509，4.037））和报告与伴侣的困难（调整OR 1.645（1.088，2.488））。局限性：在随访期间有一些样本丢失（35.1%），考虑到研究环境的动荡性质，这是预期的。调查问卷管理的措施interview.Conclusion：产后抑郁症是常见的妇女在发展中国家的设置，如南部非洲的这一部分。虽然产后抑郁症的一些风险因素与发达国家的研究中确定的相似，但存在一些重要的差异，最明显的是产前暴露于极端的社会压力。这项研究表明，在发展中国家的环境中，有可能确定怀孕期间有风险的妇女。(C)2008 Elsevier B. V.保留所有权利。
Background: Postnatal depression can have a significant impact on both maternal and child health. There have been very few studies undertaken in the developing world to identify women at risk of postnatal depression. The present study aimed to investigate risk factors for the occurrence of postnatal depression in urban South African women.Method: A large prospective Population cohort study identified antenatal risk factors for postnatal depression in Soweto, Johannesburg, South Africa. One thousand and thirty-five women were interviewed in the antenatal period and subsequently completed the Pitt Depression Questionnaire in the postnatal period.Results: 170/1035 (16.4%) women were probable cases of postnatal depression. The strongest independent predictors of postnatal depression were exposure to extreme societal stressors (witnessing a violent crime/danger of being killed) (adjusted Odds Ratio 2.468 (95% Confidence Interval 1.509, 4.037)) and reporting difficulties with their partner (adjusted OR 1.645 (1.088, 2.488)).Limitations: There was some loss of the sample during follow-up (35.1%), which was to be expected given the turbulent nature of the study setting. The measures were questionnaires administered by interview.Conclusion: Postnatal depression is common in women in developing world settings, such as this part of Southern Africa. Although some of the risk factors for postnatal depression were similar to those identified in Studies in developed nations, some important differences exist, most notably antenatal exposure to extreme societal stressors. This Study shows that it is possible to identify women at risk during pregnancy in a developing world setting. (C) 2008 Elsevier B.V. All rights reserved.