Laser direct-write for fabrication of three-dimensional paper-based devices
Laser direct-write for fabrication of three-dimensional paper-based devices
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DOI：
10.1039/c6lc00789a
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发表时间：
2016-01-01
期刊：
影响因子：
6.1
通讯作者：
Sones, C. L.
中科院分区：
文献类型：
--
作者：
He, P. J. W.;Katis, I. N.;Sones, C. L.
我们报告了基于激光的直写 (LDW) 技术的使用，该技术允许在纸质基板内设计和制造三维 (3D) 结构，从而能够通过 3D 协议实施多步骤分析测定。该技术基于激光诱导光聚合，通过调整激光功率和扫描速度等激光写入参数，我们可以控制基材内形成的疏水屏障的深度，经过精心设计和集成，可产生 3D 流动路径。到目前为止，我们已成功使用这种深度可变的图案化协议来堆叠和密封多层基板、组装二维 (2D) 侧向流动装置的背衬层，最后用于制造 3D 装置。由于还可以通过控制图案化参数，通过单个激光写入工艺来形成 3D 流动路径，因此与需要多个复杂且重复的组装程序的其他方法相比，这是一个明显的改进。因此，该技术适用于廉价、快速和大规模制造 3D 纸基微流体装置。
We report the use of a laser-based direct-write (LDW) technique that allows the design and fabrication of three-dimensional (3D) structures within a paper substrate that enables implementation of multi-step analytical assays via a 3D protocol. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depths of hydrophobic barriers that are formed within a substrate which, when carefully designed and integrated, produce 3D flow paths. So far, we have successfully used this depth-variable patterning protocol for stacking and sealing of multi-layer substrates, for assembly of backing layers for two-dimensional (2D) lateral flow devices and finally for fabrication of 3D devices. Since the 3D flow paths can also be formed via a single laser-writing process by controlling the patterning parameters, this is a distinct improvement over other methods that require multiple complicated and repetitive assembly procedures. This technique is therefore suitable for cheap, rapid and large-scale fabrication of 3D paper-based microfluidic devices.