Computing the Distribution of a Tree Metric
Computing the Distribution of a Tree Metric
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DOI:
10.1109/tcbb.2009.32
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发表时间:
2009-07-01
影响因子:
4.5
通讯作者:
Steel, Mike
中科院分区:
文献类型:
--
作者:
Bryant, David;Steel, Mike
The Robinson-Foulds (RF) distance is by far the most widely used measure of dissimilarity between trees. Although the distribution of these distances has been investigated for 20 years, an algorithm that is explicitly polynomial time has yet to be described for computing the distribution for trees around a given tree. In this paper, we derive a polynomial-time algorithm for this distribution. We show how the distribution can be approximated by a Poisson distribution determined by the proportion of leaves that lie in "cherries" of the given tree. We also describe how our results can be used to derive normalization constants that are required in a recently proposed maximum likelihood approach to supertree construction.