Inhibition of yeast respiration and fermentation by benomyl, carbendazim, isocyanates, and other fungicidal chemicals.
Inhibition of yeast respiration and fermentation by benomyl, carbendazim, isocyanates, and other fungicidal chemicals.
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苯菌灵、多菌灵、异氰酸酯和其他杀菌化学品抑制酵母呼吸和发酵。
DOI：
10.1139/m87-027
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发表时间：
1987
影响因子：
2.8
通讯作者：
D. Danić
中科院分区：
文献类型：
--
作者：
M. Chiba;A. Bown;D. Danić
研究了杀菌剂对酿酒酵母代谢的抑制作用。葡萄糖或乙醇依赖的酵母呼吸用氧电极测量，二氧化碳释放的测压测定用于测量发酵。呼吸和发酵抑制苯菌灵比相同摩尔浓度的其分解产物，多菌灵。另一种苯菌灵分解产物异氰酸丁酯比母体化合物更能抑制呼吸作用，但对发酵的抑制作用较小。在测试的异氰酸酯中，异氰酸己酯对这两种活性的抑制作用最大。克菌丹活性高于苯菌灵，异菌脲活性低于苯菌灵。由于苯菌灵在80%乙醇中制备时迅速分解为多菌灵，因此当将其加入酵母中以确定其对呼吸或发酵的影响时，只有59%的溶解苯菌灵是完整的。
The inhibition of yeast (Saccharomyces cerevesiae) metabolism by fungicidal chemicals was investigated. Glucose- or ethanol-dependent yeast respiration was measured with an oxygen electrode, and manometric determination of carbon dioxide release was used to measure fermentation. Both respiration and fermentation were inhibited more by benomyl than by identical molar concentrations of its breakdown product, carbendazim. Butyl isocyanate, another benomyl breakdown product, inhibited respiration more but inhibited fermentation less than the parent compound. Of the isocyanates tested, hexyl isocyanate was the most inhibitory towards both activities. Captan was more active and iprodione less active than benomyl. Because benomyl rapidly broke down to carbendazim when it was prepared in 80% ethanol, only 59% of the dissolved benomyl was intact when it was added to yeast to determine its effect on respiration or fermentation.