Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome -: Patient selection for fetal intervention

Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome -: Patient selection for fetal intervention
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DOI:
10.1161/circulationaha.105.588194
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发表时间:
2006-03-21
期刊:
影响因子:
37.8
通讯作者:
Tworetzky, W
Tworetzky, W
中科院分区:
医学1区
文献类型:
--
作者:
Mäkikallio, K;McElhinney, DB;Tworetzky, W

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背景-胎儿主动脉瓣成形术可以防止主动脉瓣狭窄发展为左心发育不良综合征.预测哪些AS胎儿将发展HLHS对于优化胎儿干预的患者选择至关重要。本研究的目的是确定与妊娠中期胎儿AS进展为HLHS相关的超声心动图特征。方法和结果:回顾了43例诊断为AS且左心室(LV)长度正常的胎儿超声心动图,
Background - Fetal aortic valvuloplasty may prevent progression of aortic stenosis ( AS) to hypoplastic left heart syndrome (HLHS). Predicting which fetuses with AS will develop HLHS is essential to optimize patient selection for fetal intervention. The aim of this study was to define echocardiographic features associated with progression of midgestation fetal AS to HLHS.Methods and Results - Fetal echocardiograms were reviewed from 43 fetuses diagnosed with AS and normal left ventricular (LV) length at