PENICILLIN-INDUCED INTERICTAL DISCHARGES FROM CAT HIPPOCAMPUS .2. MECHANISMS UNDERLYING ORIGIN AND RESTRICTION

PENICILLIN-INDUCED INTERICTAL DISCHARGES FROM CAT HIPPOCAMPUS .2. MECHANISMS UNDERLYING ORIGIN AND RESTRICTION
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DOI:
10.1152/jn.1969.32.5.663
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发表时间:
1969-01-01
影响因子:
2.5
通讯作者:
SPENCER, WA
SPENCER, WA
中科院分区:
医学3区
文献类型:
--
作者:
DICHTER, M;SPENCER, WA

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方法本研究中使用的方法与前一篇论文中描述的方法相同(17)。采用的唯一特殊手术是穹窿传入神经切断术。在实验中消除穹窿中的传入纤维作为研究复发性锥体细胞通路的方法的可行性和实用性已经得到证实(46)。此外,同样的方法最近也被应用于小脑皮层的研究(20)。在进行急性实验前至少3周,将一个海马部分暴露,并在直视下使用烧灼或细剃刀刀片银片切割穹窿和海马连合。(The烧灼术似乎比刀更上级,因为它产生的
METHODSThe methods used in this study were the same as those described in the previous paper (17). The only special procedure employed was deafferentation of the fornix. The feasibility and utility of experimentally eliminating the afferent fibers in the fornix as a method for studying recurrent pyramidal cell pathways has been demonstrated(46). Moreover, the same method has been applied more recently to studies of the cerebellar cortex (20). At least 3 weeks before acute experiments were carried out, one hippocampus was partially exposed and a cautery or fine razor blade sliver was used to cut the fornix and the hippocampal commissure under direct vision.(The cautery seemed superior to a knife as it produced less