Computer-Assisted Evaluation of Contrast Kinetics for Detection of Hepatocellular Carcinoma on Magnetic Resonance Imaging
Computer-Assisted Evaluation of Contrast Kinetics for Detection of Hepatocellular Carcinoma on Magnetic Resonance Imaging
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DOI：
10.1067/j.cpradiol.2014.07.004
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发表时间：
2015-01-01
影响因子：
1.4
通讯作者：
Maki, Jeffrey H.
中科院分区：
文献类型：
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作者：
Chaturvedi, Abhishek;Bhargava, Puneet;Maki, Jeffrey H.
本研究的目的是评估使用半定量对比增强参数分析作为改善肝硬化患者肝细胞癌（HCC）磁共振（MR）评估的客观标准。使用专用肝脏图像后处理工作站对19例经病理证实的21例HCC患者的磁共振增强检查结果进行评估。为每个病变创建对比增强动力学曲线，并从信号强度-时间图中定义4个增强参数（动脉冲洗斜率、动脉-门静脉斜率、动脉-平衡斜率和门静脉平衡斜率）。评估HCC特征的每个增强参数的准确性。统计分析显示，动脉相冲洗斜率百分比值bbb1.35 /秒的敏感性为86%，特异性为71%，准确性为79%，而动脉平衡冲刷斜率百分比值则正确表征HCC
The purpose of this study was to assess the use of semiquantitative contrast-enhanced parameter analysis as an objective criteria for improving the magnetic resonance (MR) evaluation of hepatocellular carcinoma (HCC) in patients with cirrhosis. Contrast-enhanced MR examination findings from 19 patients with 21 pathologically proven HCC were evaluated using a dedicated liver image postprocessing workstation. Contrast-enhancement kinetic curves were created for each lesion, and 4 enhancement parameters (arterial wash-in slope, arterial-portal slope, arterial-equilibrium slope, and portal-equilibrium slope) were defined from the signal intensity-time plots. The accuracy of each enhancement parameter for the characterization of HCC was assessed. Statistical analysis revealed that an arterial-phase wash in slope percentage value > 1.35 per sec had a sensitivity of 86%, a specificity of 71%, and an accuracy of 79% for the correct characterization of HCC, whereas an arterial equilibrium wash-out slope percentage value