Comparison of ECG-gated rectilinear vs. real-time radial K-space sampling schemes in cine true-FISP cardiac MRI
Comparison of ECG-gated rectilinear vs. real-time radial K-space sampling schemes in cine true-FISP cardiac MRI
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DOI：
10.1081/jcmr-200036124
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发表时间：
2004-01-01
影响因子：
6.4
通讯作者：
Lewin, JS
中科院分区：
文献类型：
--
作者：
Boll, DT;Merkle, EM;Lewin, JS
目的。比较电影 True-FISP 心脏磁共振成像中的三种 k 空间采样方案，并评估计算的定量功能心脏参数作为基础 k 空间采样技术的函数的变化。材料和方法。使用 1.5 T MR 成像系统（Magnetom Sonata，西门子医疗解决方案，埃尔兰根，德国），三个 k 空间数据采样方案：直线（2.96 ms/1.58 ms/70 度/12 s TR/TE/FA/AcquisitionTime）和两个径向 k 空间采集，带滤波反投影 (RADIAL) (2.45 ms/1.25) ms/50°/3.3 s TR/TE/FA/AT) 和 True-FISP 序列的稳态投影成像与动态回声读出 (SPIDER) (339 ms/1.62 ms/55°/1.8 s TR/TE/FA/AT) 应用于 10 名健康志愿者。获取长轴和短轴屏气序列，并确定血液和心肌的信噪比（SNR）以及对比噪声比（CNR）。定量心脏功能分析包括：收缩末期/舒张末期容积、射血分数和左心室质量的测定。由两名独立的读者对每个志愿者和 k 空间采样策略进行三次功能分析。统计分析评估了从三种采样技术中每一种获得的测量的准确性以及观察者内和观察者间的可靠性。结果。功能数据的观察者内和观察者间可靠性测量是同质的，没有统计学上的显着差异。观察者内相关系数范围为 0.94-0.99；观察者间相关系数范围为 0.97-0.99。 SPIDER 和 RADIAL 采样的 True-FISP 序列的直接比较显示，测量的功能参数没有统计学上的显着差异，研究间相关系数为 0.88-0.98。 RADIAL 和 SPIDER 图像具有更好的时间分辨率，并且经过定性判断以提供卓越的壁/血液边界清晰度。当将直线采样采集的结果与径向或 SPIDER 采样技术进行比较时，在每个体积功能参数中发现了统计学上的显着差异。 RADIAL 和 SPIDER 结果始终高于从直线数据集获得的体积测量结果。结论。采用更快的采样方案可以增强信号均匀性，同时保持估计功能心脏参数所需的 CNR。增强的信号均匀性和维持的 CNR 将很可能提高心脏功能参数确定的准确性。
Purpose. To compare three k-space sampling schemes in cine True-FISP cardiac magnetic resonance imaging and to evaluate changes in calculated quantitative functional cardiac parameters as a function of underlying k-space sampling techniques. Material and Methods. Using a 1.5 T MR imaging system (Magnetom Sonata, Siemens Medical Solutions, Erlangen, Germany), three k-space data-sampling schemes: rectilinear (2.96 ms/1.58 ms/70degrees/12 s TR/TE/FA/AcquisitionTime), and two radial k-space acquisitions, with filtered back-projection (RADIAL) (2.45 ms/1.25 ms/50degrees/3.3 s TR/TE/FA/AT), and steady-state projection imaging with dynamic echotrain readout (SPIDER) (339 ms/1.62 ms/55degrees/1.8 s TR/TE/FA/AT) of a True-FISP sequence were applied in 10 healthy volunteers. Long- and short-axis breath-hold series were acquired and signal-to-noise ratios (SNR) for blood and myocardium were determined, as was contrast-to-noise ratios (CNR). Quantitative cardiac functional analysis included: determination of end-systolic/end-diastolic volumes, ejection fraction, and left ventricular mass. Functional analysis was performed by two independent readers three times for each volunteer and k-space sampling strategy. Statistical analysis evaluated the accuracy of the measurements obtained from each of the three sampling techniques and the intra- and interobserver reliability. Results. Intraobserver and interobserver reliability measures of functional data were homogeneous without statistically significant differences. Intraobserver correlation coefficients ranged from 0.94-0.99; interobserver correlation coefficients ranged from 0.97-0.99. Direct comparison of SPIDER- and RADIAL-sampled True-FISP sequences showed no statistically significant differences in measured functional parameters with interstudy correlation coefficients from 0.88-0.98. RADIAL and SPIDER images had better temporal resolution and were qualitatively judged to provide superior wall/blood border definition. Statistically significant differences were identified in each volumetric functional parameter when results from the rectilinear sampling acquisitions were compared with either radial or SPIDER sampling techniques. RADIAL and SPIDER results were consistently higher than volumetric measures obtained from the rectilinear data set. Conclusion. Employing faster sampling schemes led to enhanced signal homogeneity while maintaining the necessary CNR for estimation of functional cardiac parameters. Enhanced signal homogeneity and maintained CNR will most likely improve the accuracy of the cardiac functional parameter determination.