Current challenges in implementing cell-derived influenza vaccines: Implications for production and regulation, July 2007, NIBSC, Potters Bar, UK
Current challenges in implementing cell-derived influenza vaccines: Implications for production and regulation, July 2007, NIBSC, Potters Bar, UK
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DOI：
10.1016/j.vaccine.2009.02.064
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发表时间：
2009-05-14
期刊：
影响因子：
5.5
通讯作者：
Krause, Ryoko
中科院分区：
文献类型：
--
作者：
Minor, Philip D.;Engelhardt, Othmar G.;Krause, Ryoko
2007年7月在英国NIBSC举行了一次会议，讨论在使用细胞培养系统生产流感疫苗方面取得进展的影响。讨论的问题包括在菌株选择中使用鸡蛋和不同细胞类型的影响、用于生产的种子病毒的发展以及用于确定疫苗效力的试剂的性质。展望了该领域未来的研究进展。
A meeting was held at NIBSC, UK in July 2007 to discuss the implications of progress in the use of cell culture systems for the manufacture of vaccines against influenza. Issues discussed included the effect of using eggs and different cell types in strain selection, development of seed viruses to be used in production and the nature of the reagents to be used in determining vaccine potency. Future studies to progress the field were reviewed.