Sedentary Behavior in the First Year After Stroke: A Longitudinal Cohort Study With Objective Measures

Sedentary Behavior in the First Year After Stroke: A Longitudinal Cohort Study With Objective Measures
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DOI:
10.1016/j.apmr.2014.08.015
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发表时间:
2015-01-01
影响因子:
4.3
通讯作者:
Chastin, Sebastien
Chastin, Sebastien
中科院分区:
医学1区
文献类型:
--
作者:
Tieges, Zoe;Mead, Gillian;Chastin, Sebastien

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目的:量化久坐行为的纵向变化设计:对急性卒中患者进行纵向队列研究,随访时间超过1年,地点:急性教学医院或门诊,以及出院后的社区。急性脑卒中患者的方便样本(N = 96;中位年龄,72岁,四分位距[IQR] = 64- 80岁; 67%男性;中位国立卫生研究院卒中量表评分= 2,IQR = 1-3),在卒中后1、6和12个月进行评估。干预:不适用。主要结果测量:久坐行为花费时间的数量和模式的客观测量:总久坐时间,加权中位数久坐回合长度和碎片指数。结果:中风幸存者高度久坐,平均每天81%的时间花费在久坐行为上:第1、6和12个月时的中位数分别为19.9小时(IQR = 18.4- 22.1小时)、19.1小时(17.8- 20.8小时)和19.3小时(17.3- 20.9小时)。久坐行为的纵向变化采用线性混合效应模型进行估计。协变量为年龄、性别、卒中严重程度(国立卫生研究院卒中量表评分)、体能(6分钟步行距离)和功能独立性(诺丁汉日常生活扩展活动问卷评分)。脑卒中严重程度越高,功能独立性越差,久坐行为越多(β = .11,SE = .05,P = .020和β = -.11,SE = .01,P
Objective: To quantify longitudinal changes in sedentary behavior (ie, nonexercise seated or lying behavior) after stroke to ascertain whether reducing sedentary behavior might be a new therapeutic target.Design: Longitudinal cohort study of patients with acute stroke who were followed over 1 year.Setting: Acute teaching hospital or outpatient clinic, and the community after discharge.Participants: A convenience sample of patients with acute stroke (N = 96; median age, 72y, interquartile range [IQR] = 64-80y; 67% men; median National Institute of Health Stroke Scale score = 2, IQR = 1-3) who were assessed at 1, 6, and 12 months after stroke.Interventions: Not applicable.Main Outcome Measures: Objective measures of amount and pattern of time spent in sedentary behavior: total sedentary time, weighted median sedentary bout length, and fragmentation index.Results: Stroke survivors were highly sedentary, spending on average 81% of the time per day in sedentary behavior: median=19.9 hours (IQR = 18.4-22.1h), 19.1 hours (17.8-20.8h), and 19.3 hours (17.3-20.9h) at 1, 6, and 12 months, respectively. Longitudinal changes in sedentary behavior were estimated using linear mixed effects models. Covariates were age, sex, stroke severity (National Institute of Health Stroke Scale score), physical capacity (6-minute walk distance), and functional independence (Nottingham Extended Activities of Daily Living Questionnaire score). Higher stroke severity and less functional independence were associated cross-sectionally with more sedentary behavior (beta = .11, SE = .05, P = .020 and beta = -.11, SE = .01, P