Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin
Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin
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DOI：
10.1016/j.cclet.2013.03.032
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发表时间：
2013-06
影响因子：
9.1
通讯作者：
Ke-Rang Wang;Hong-Wei An;Dan Han;Feng Qian;Xiao-liu Li
中科院分区：
文献类型：
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作者：
Ke-Rang Wang;Hong-Wei An;Dan Han;Feng Qian;Xiao-liu Li
合成了一种新的三氮杂蒽荧光糖簇，并通过荧光光谱、圆二色光谱和浊度法研究了其与PNA凝集素的选择性结合作用。该糖簇对PNA凝集素表现出很强的结合亲和力，Stern-Volmer猝灭常数为5.8× 105 mol − 1 L。
A novel triazatruxene-based fluorescent glycocluster was synthesized and its selective binding interactions with PNA lectin were investigated by fluorescence spectroscopy, CD spectroscopy, and a turbidity assay. The glycocluster exhibited a strong binding affinity for PNA lectin with a Stern–Volmer quenching constant of 5.8×105mol−1L.