Gloves and dermal exposure to chemicals: Proposals for evaluating workplace effectiveness
Gloves and dermal exposure to chemicals: Proposals for evaluating workplace effectiveness
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DOI：
10.1093/annhyg/meh060
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发表时间：
2004-10-01
影响因子：
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通讯作者：
Brouwer, D
中科院分区：
文献类型：
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作者：
Cherrie, JW;Semple, S;Brouwer, D
化学防护手套有标准化的实验室测试，可提供突破时间和稳态渗透通量的估计。然而，有证据表明这些测试可能与工作场所的手套使用并不完全相关。尽管有一些研究试图测量化学防护手套的有效性，但对于如何评估手套工作场所的有效性尚未达成共识。我们使用皮肤暴露的概念模型来帮助分析工人在戴手套时皮肤可能如何暴露，并提出了一种新的手套工作场所防护系数（PFgloves），该系数基于不戴手套的手估计的化学物质吸收量与戴防护手套的手部的化学物质吸收量的比率。数学模拟表明，对于某种手套类型来说，手套防护系数不太可能是恒定的，而是会受到工作环境和暴露时间的强烈影响。这对于防护手套的选择具有重要影响。
There are standardized laboratory tests for chemical protective gloves that provide estimates of breakthrough time and steady-state permeation flux. However, there is evidence to suggest that these tests may not be completely relevant to glove usage in the workplace. There is no consensus about how glove workplace effectiveness should be assessed, although a few studies have attempted to measure the effectiveness of chemical protective gloves. We have used a conceptual model of dermal exposure to help analyse how workers' skin may become exposed while wearing gloves, and propose a new glove workplace protection factor (PFgloves), which is based on the ratio of the estimated uptake of chemicals through the hands without gloves to the uptake through the hands while wearing protective gloves. Mathematical simulations demonstrate that glove protection factor is unlikely to be constant for a glove type, but will be strongly influenced by the work situation and the duration of the exposure. This has important consequences for the selection of protective gloves.