TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes.
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes.
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TransFac及其模块移植：真核生物中的转录基因调节。
DOI：
10.1093/nar/gkj143
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发表时间：
2006-01-01
影响因子：
14.9
通讯作者：
Wingender E
中科院分区：
文献类型：
--
作者：
Matys V;Kel-Margoulis OV;Fricke E;Liebich I;Land S;Barre-Dirrie A;Reuter I;Chekmenev D;Krull M;Hornischer K;Voss N;Stegmaier P;Lewicki-Potapov B;Saxel H;Kel AE;Wingender E
转录因子，其结合位点，核丁基分布材料和调节基因以及复合元素的补充数据库Transcompel®的TransFac®数据库已在各种级别上进一步增强。 ™和Patch™为TransFac®提供了增加的功能。 HGNC，MGI和RGD分别用于人类，小鼠和大鼠基因，借助于Intersoscan，PFAM，SMART和PROSITE域，也将自动分配给Transcroply®的蛋白质序列。强制表，一个单独的表，以详细的信息，以了解复合元素的实验证据，最终用于TransFac®，特别是果蝇转录因子结合位点的增益（由果蝇的增益必须强调DNASE I足迹数据库）和拟南芥的因素（由DATF提供，拟南芥的数据库）。
The TRANSFAC® database on transcription factors, their binding sites, nucleotide distribution matrices and regulated genes as well as the complementing database TRANSCompel® on composite elements have been further enhanced on various levels. A new web interface with different search options and integrated versions of Match™ and Patch™ provides increased functionality for TRANSFAC®. The list of databases which are linked to the common GENE table of TRANSFAC® and TRANSCompel® has been extended by: Ensembl, UniGene, EntrezGene, HumanPSD™ and TRANSPRO™. Standard gene names from HGNC, MGI and RGD, are included for human, mouse and rat genes, respectively. With the help of InterProScan, Pfam, SMART and PROSITE domains are assigned automatically to the protein sequences of the transcription factors. TRANSCompel® contains now, in addition to the COMPEL table, a separate table for detailed information on the experimental EVIDENCE on which the composite elements are based. Finally, for TRANSFAC®, in respect of data growth, in particular the gain of Drosophila transcription factor binding sites (by courtesy of the Drosophila DNase I footprint database) and of Arabidopsis factors (by courtesy of DATF, Database of Arabidopsis Transcription Factors) has to be stressed. The here described public releases, TRANSFAC® 7.0 and TRANSCompel® 7.0, are accessible under .
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影响因子：
14.9
作者：
Chekmenev DS;Haid C;Kel AE
通讯作者：
Kel AE
影响因子：
14.9
作者：
Hulo, N;Sigrist, CJA;Bairoch, A
通讯作者：
Bairoch, A
影响因子：
14.9
作者：
Wheeler, David L.;Barrett, Tanya;Yaschenko, Eugene
通讯作者：
Yaschenko, Eugene
影响因子：
14.9
作者：
Kel-Margoulis, OV;Kel, AE;Wingender, E
通讯作者：
Wingender, E
影响因子：
5.8
作者：
Bergman, CM;Carlson, JW;Celniker, SE
通讯作者：
Celniker, SE