The effects of V4 and middle temporal (MT) area lesions on visual performance in the rhesus monkey
The effects of V4 and middle temporal (MT) area lesions on visual performance in the rhesus monkey
复制标题
DOI：
10.1017/s0952523800005423
复制
发表时间：
1993-07
影响因子：
1.9
通讯作者：
Peter H. Schiller
中科院分区：
文献类型：
--
作者：
Peter H. Schiller
摘要V4、MT和V4+MT联合病变的影响在广泛的视觉能力上进行了评估，包括对比敏感度、波长和亮度辨别力、形状视觉、模式视觉、运动和闪烁感知、立体视觉和选择比刺激阵列中出现的刺激不突出的刺激。观察到的主要缺陷是在V4病变后，选择这种不太突出的刺激的能力的损失，这是无论刺激阵列是可见的方式，使用亮度，色度，运动，或立体深度作为表面媒体的情况。此外，V4病变产生轻度缺陷的颜色，亮度和形式的视觉，而MT病变产生轻度至中度缺陷的运动和闪烁的感觉。这两种病变都产生了轻度的对比敏感度缺陷，从运动感知形状，并在许多任务中产生了反应时间增加。V4和MT合并病变导致的损害不大于任一病变的缺陷之和。没有一个病变产生明显的立体视觉缺陷。研究结果表明：（1）V4区是神经系统的一部分，参与从视觉场景中提取刺激，这些刺激在视觉系统中引起的神经活动比其他刺激少;（2）其他几个纹外区和不止两个主要的皮层处理流有助于纹外皮层处理基本的视觉功能。
Abstract The effects of V4, MT, and combined V4+MT lesions were assessed on a broad range of visual capacities that included measures of contrast sensitivity, wavelength and brightness discrimination, form vision, pattern vision, motion and flicker perception, stereopsis, and the selection of stimuli that were less prominent than those with which they appeared in stimulus arrays. The major deficit observed was a loss in the ability, after V4 lesions, to select such less prominent stimuli; this was the case irrespective of the manner in which the stimulus arrays were made visible, using either luminance, chrominance, motion, or stereoscopic depth as surface media. In addition, V4 lesions yielded mild deficits in color, brightness, and form vision whereas MT lesions yielded mild to moderate deficits in motion and flicker perception. Both lesions produced mild deficits in contrast sensitivity, shape-from-motion perception, and yielded increased reaction times on many of the tasks. The impairment resulting from combined V4 and MT lesions was not greater than the sum of the deficits of either lesion. None of the lesions produced significant deficits in stereopsis. The findings suggest that (1) area V4 is part of a neural system that is involved in extracting stimuli from the visual scene that elicit less neural activity early in the visual system than do other stimuli with which they appear and (2) several other extrastriate regions and more than just two major cortical processing streams contribute to the processing of basic visual functions in the extrastriate cortex.