CEREBELLOFUGAL PROJECTIONS IN BRACHIUM CONJUNCTIVUM OF RAT .1. CONTRALATERAL ASCENDING PATHWAY
CEREBELLOFUGAL PROJECTIONS IN BRACHIUM CONJUNCTIVUM OF RAT .1. CONTRALATERAL ASCENDING PATHWAY
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DOI：
10.1002/cne.901780307
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发表时间：
1978-01-01
影响因子：
2.5
通讯作者：
CARMAN, JB
中科院分区：
文献类型：
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作者：
FAULL, RLM;CARMAN, JB
使用 Fink-Heimer 技术对 23 只动物的大鼠结膜臂 (BC) 对侧上升通路中的小脑投射进行了研究，以证明完全 BC 病变 (7)、部分 BC 病变 (14) 和 BC 背侧对照病变 (2) 导致的轴突变性。所有因 BC 周围结构的伴随参与而导致的变性均根据已知的纤维路径和对照实验的结果进行了解释。对侧上升通路从 BC 交汇处沿嘴部上升，通过腹内侧中脑被盖到达间脑。在中脑中，小脑纤维在整个红核（包括小核）中大量终止，而其他纤维则从升束穿过背外侧和背内侧，终止于相邻的中脑核。背外侧定向纤维终止于中脑网状结构、上丘深灰层、前顶盖核和后连合核；背侧定向纤维终止于主动眼神经核、Darkschewitsch 核、Cajal 间质核和中央灰质。相当数量的小脑纤维在红前区域内更多地向嘴部前进，并通过 2 条途径进入丘脑。大多数遵循 Forel 区域 H 内的直接下丘脑走行，并在向未定带贡献纤维后，进入丘脑腹内侧核 (Vm) 的尾极，终止于整个 Vm 和腹外侧复合体 (VI)。其他的通过内髓膜进入并终止于束旁核和中央外侧核。少数小脑丘脑纤维形成对侧 V1 的连合投影。小脑丘脑向腹侧核的投射分布在整个 Vm 和 V1 的发现表明，Vm-V1 复合体是大鼠灵长类丘脑腹侧前核和腹侧外侧核的同源物。
The cerebellofugal projections in the contralateral ascending pathway of the brachium conjunctivum (BC) in the rat were investigated in 23 animals using the Fink-Heimer technique to demonstrate the axonal degeneration resulting from complete BC lesions (7), partial BC lesions (14) and control lesions dorsal to the BC (2). All of the degeneration resulting from the concomitant involvement of the structures surrounding the BC was accounted for in terms of known fiber pathways and from the results in the control experiments. The contralateral ascending pathway ascends rostrally from the decussation of the BC through the ventromedial midbrain tegmentum to the diencephalon. In the midbrain, cerebellofugal fibers terminate heavily throughout the red nucleus including the nucleus minimus, while others pass dorsolaterally and dorsomedially from the ascending tract to terminate in adjacent midbrain nuclei. The dorsolaterally directed fibers terminate in the midbrain reticular formation, the stratum griseum profundum of the superior colliculus, the anterior pretectal nucleus and the nucleus of the posterior commissure; the dorsomedially directed fibers terminate in the principal oculomotor nucleus, the nucleus of Darkschewitsch, interstitial nucleus of Cajal and the central gray matter. A considerable number of the cerebellofugal fibers proceed more rostrally within the prerubral field and enter the thalamus by 2 routes. Most follow a direct subthalamic course within field H of Forel and after contributing fibers to the zona incerta, enter the caudal pole of the ventromedial nucleus (Vm) of the thalamus to terminate throughout Vm and the ventrolateral complex (VI). Others enter via the internal medullary lamina and terminate throughout the parafascicular and central lateral nuclei. A small number of cerebellothalamic fibers form a commissural projection to V1 on the opposite side. The finding that the cerebellothalamic projections to the ventral nucleus are distributed throughout Vm and V1 establishes the Vm-V1 complex as the homologue in the rat of the ventral anterior and ventral lateral nuclei in the primate thalamus.